Clinical trial · Interventional
Photodynamic Therapy of Actinic Keratosis of the Face and Scalp With and Without Prior Curettage
NCT03697590CI-TRIAL-00035173completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Guidelines for photodynamic therapy (PDT) of actinic keratosis recommend pretreatment with curettage. The impact of curettage on the treatment effect is, however, not known. The present study aimed to evaluate whether daylight-PDT without curettage would reduce treatment effect compared to daylight-PDT with curettage.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Keratosis, Actinic | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Curettage | Drug | — | UNRESOLVED |
| No curettage | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PDT with no curettage
- interventionNames
- Drug: No curettage
- type
- ACTIVE_COMPARATOR
- label
- Standard PDT
- interventionNames
- Drug: Curettage
Primary outcomes (1)
- measure
- Complete lesion response rate
- timeFrame
- Treatment efficacy was evaluated 3 months after PDT
- description
- Complete lesion response rate, was defined as the number of completely responding lesions divided by the total number of treated lesion in each field. Complete lesion response was defined as complete disappearance of the lesion both by palpation and visually.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: \- Multiple actinic keratosis on the forehead or scalp Exclusion Criteria: * Known allergy to methyl aminolevulinate * Porphyria * Pregnancy * Lactation
References
Publications (0)
Data not yet available
No reference posted for this study.