Clinical trial · Interventional
Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers
NCT03683680CI-TRIAL-00110330recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research study is evaluating a new method for determining stage and prognosis of individuals with malignant pleural mesothelioma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mesothelioma | Malignant Mesothelioma | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CLDN15/VIM Test | Other | — | UNRESOLVED |
| MPT Test | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- MRiS
- description
- * The specimens to be collected will include at least five pleural biopsy samples * MPT test and the CLDN15/VIM test will be performed
- interventionNames
- Other: MPT Test
- Other: CLDN15/VIM Test
Primary outcomes (1)
- measure
- Pre-treatment Prognostic Algorithm Validation
- timeFrame
- 4 years
- description
- The primary objective is to utilize a novel prognostic algorithm to predict the outcome of MPM patients. This algorithm includes 4 different tests: molecular, radiological, and blood based. It will be performed on 240 prospectively-collected samples. A score of 0-4 will be assigned to each patient and the data will be analyzed by a statistician
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All adult patients with a diagnosis of malignant pleural mesothelioma undergoing * diagnostic pleural biopsy * pleuroscopy * and/or VATS resections * Participants must be 18 years of age or older. Exclusion Criteria: -Any patient who is found to be unsuitable for * surgery, * treatment * diagnosis,
References
Publications (0)
Data not yet available
No reference posted for this study.