Clinical trial · Interventional
Zero-ischemia Robot-assisted Partial Nephrectomy Using Near-infrared Fluorescence
Zero-ischemia Robot-assisted Partial Nephrectomy Using Near-infrared Fluorescence: A Prospective, Monocentric, Randomized, Comparative and Open-label Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with renal cancer are commonly treated by robot-assisted partial nephrectomy. Renal artery clamping is commonly required inducing kidney ischemia during surgery. It impacts parenchymal and renal function. This study aims to compare a new surgical procedure in order to reduce ischemia effect and preserve renal function after partial nephrectomy for renal tumour.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Robot assisted partial nephrectomy super-selective clamping | Procedure | — | UNRESOLVED |
| Robot assisted partial nephrectomy with renal artery clamping | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Robot assisted partial nephrectomy super-selective clamping
- description
- The Da Vinci robot (device) allows to use near-infrared fluorescence in order to clamp precisely the branches of the vascularization for the partial nephrectomy. The healthy parenchyma ischemia is avoided.
- interventionNames
- Procedure: Robot assisted partial nephrectomy super-selective clamping
- type
- ACTIVE_COMPARATOR
- label
- Robot assisted partial nephrectomy with renal artery clamping
- description
- The partial nephrectomy with robotic assistance is performed using a renal artery. It's the conventional method.
- interventionNames
- Procedure: Robot assisted partial nephrectomy with renal artery clamping
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * candidate for a robot-assisted partial nephrectomy for renal tumour * patient affiliated to social security * signature of the informed consent Exclusion Criteria: * proven or suspected allergy to the indocyanine green * coagulation disorder contraindicating robot assistance in the partial nephrectomy * medical pathology contraindicating pneumo-peritoneum * multiple tumors * horseshoe kidney * exclusion period of another interventionnal study * protected person referred to in Articles L1121-5 to L1121-8 of the Code of Public Health
References
Publications (1)
- DERIVEDLong JA, Fiard G, Giai J, Teyssier Y, Fontanell A, Overs C, Poncet D, Descotes JL, Rambeaud JJ, Moreau-Gaudry A, Ittobane T, Bouzit A, Bosson JL, Lanchon C. Superselective Ischemia in Robotic Partial Nephrectomy Does Not Provide Better Long-term Renal Function than Renal Artery Clamping in a Randomized Controlled Trial (EMERALD): Should We Take the Risk? Eur Urol Focus. 2022 May;8(3):769-776. doi: 10.1016/j.euf.2021.04.009. Epub 2021 Apr 27. PMID 33931361