Clinical trial · Interventional
Fertility Preservation With Ovarian Tissue Freezing
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to obtain ovarian tissue from female patients undergoing gonadotoxic treatments or gonadal ablating surgery, and that in consequence may see their future fertility impaired. Participants will be offered to preserve (freeze) and use ovarian tissue for the purpose of conceiving in the future. Although, 86 live births have been reported with ovarian tissue cryo-preservation and grafting, the procedure is still considered experimental. This research, will help us to learn and validate how to perform ovarian tissue cryo-preservation and thawing in the fertility preservation context.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Hematologic Disorder | — | UNRESOLVED | — |
| Infertility | — | UNRESOLVED | — |
| Ovarian Failure | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ovarian Cryopreservation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Cryopreservation of ovarian tissu by vitrification
- timeFrame
- 5 years
- description
- Measure the fertility rate of cryopreservation and grafting by ovarian tissue vitrification.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 2 Months
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Females, \> 2 month and \< 18 years of age 2. Undergo surgery, chemotherapy, drug treatment, and/or radiation for the treatment or prevention of a medical condition or malignancy expected to result in permanent and complete loss of subsequent ovarian function. 3. Or, have a medical condition or malignancy that requires removal of all or part of one or both ovaries. 4. Subject may have newly diagnosed or recurrent disease. 5. Subject who already has stored cryopreserved ovarian tissue in a frozen state prior to undergoing cancer treatments (surgery, chemotherapy or radiation) will be eligible for enrolment with informed consent. 6. Subject not eligible to standard fertility preservation 7. The subject and/or the subject's legally authorized guardian must acknowledge in writing that consent for specimen collection has been obtained, in accordance with institutional policies. Exclusion Criteria: 1. Women with psychological, psychiatric or other conditions which prevent giving fully informed consent. 2. Women whose underlying medical condition significantly increases their risk of complications from anesthesia and surgery. 3. Women to whom the research intervention may decrease the survival or the treatment response to the underlying disease. 4. AMH (Anti Müllerian Hormone) \<0.016 ng/dl 5. Women whose surgery is preformed outside the CHU Ste-Justine 6. Patients eligible to a standard fertility preservation procedure. \-
References
Publications (0)
Data not yet available