Clinical trial · Interventional
Application of Linked Color Imaging(LCI) in Diagnosis of Early Gastric Cancer(EGC)
Application of Linked Color Imaging(LCI) in Diagnosis of Early Gastric Cancer(EGC): a Multicenter,Prospective, Randomized Controlled Study
NCT03661671CI-TRIAL-00034744unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
the purpose of this study is to evaluate application value of LCI in the diagnosis of early gastric cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early Gastric Cancer | Early Gastric Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LCI+white light | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- LCI+white light
- description
- Using white light firstly to observe from cardia to duodenum and then switch LCI model to observe from antrum to cardia
- interventionNames
- Diagnostic Test: LCI+white light
- type
- NO_INTERVENTION
- label
- White light
- description
- Using white light only.
Primary outcomes (1)
- measure
- Detection rate of gastric neoplastic lesion
- timeFrame
- immediately following the procedure
- description
- Include early gastric caner,high grade dysplasia low grade dysplasia and adenoma
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. High-risk group of gastric cancer: H. pylori infection; previously suffering from chronic atrophic gastritis, intestinal metaplasia, gastric ulcer, gastric polyps, residual stomach after surgery, hypertrophic gastritis, malignant anemia and other precancerous diseases of gastric cancer; 2. First degree relatives of patients with gastric cancer; 3. There are other high risk factors for gastric cancer (high salt, salted diet, smoking, heavy drinking, etc.). 4. Patients with early gastric cancer treated with endoscopic therapy (ESD, EMR). 5. The informed consent has been signed. Exclusion Criteria: 1. The TNM classification of cancer is consistent with those diagnosed by T2 above. 2. Patients with abnormal blood coagulation function or taking anticoagulants can not biopsy. 3. There were contraindications for gastroscopy. 4. A patient without self judgement; 5. Those who did not sign informed consent. 6. Previous gastroscopy has found suspicious lesions requiring careful examination.
References
Publications (3)
- RESULTFukuda H, Miura Y, Hayashi Y, Takezawa T, Ino Y, Okada M, Osawa H, Lefor AK, Yamamoto H. Linked color imaging technology facilitates early detection of flat gastric cancers. Clin J Gastroenterol. 2015 Dec;8(6):385-9. doi: 10.1007/s12328-015-0612-9. Epub 2015 Nov 11. PMID 26560036
- RESULTOkada M, Sakamoto H, Takezawa T, Hayashi Y, Sunada K, Lefor AK, Yamamoto H. Laterally Spreading Tumor of the Rectum Delineated with Linked Color Imaging Technology. Clin Endosc. 2016 Mar;49(2):207-8. doi: 10.5946/ce.2015.077. Epub 2016 Feb 12. No abstract available. PMID 26867550
- RESULTSun X, Dong T, Bi Y, Min M, Shen W, Xu Y, Liu Y. Linked color imaging application for improving the endoscopic diagnosis accuracy: a pilot study. Sci Rep. 2016 Sep 19;6:33473. doi: 10.1038/srep33473. PMID 27641243