Clinical trial · Interventional
Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors
NCT03650322CI-TRIAL-00067778completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators propose to compare the effects of a 12-week, supervised, site-based group yoga intervention on cognitive function, functional fitness, and well-being in middle-aged cancer survivors. Subjects will be randomly assigned to one of three exercise conditions: a yoga group, an aerobic walking group or a strength training group. All sessions (2-3 times per week) will be led by a trained exercise leader for a total of 150 minutes of exercise each week for the 12-week intervention.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Cancer-related Problem/Condition | — | UNRESOLVED | — |
| Exercise | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic Walking | Behavioral | — | UNRESOLVED |
| Stretching and Toning | Behavioral | — | UNRESOLVED |
| Yoga | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Yoga Practice
- description
- Participants will be led through a beginner yoga course taught by a certified yoga instructor. Classes will meet twice a week for 75 minutes each for the duration of 12 weeks. Sessions will focus on yoga postures, breathing, and meditative practices and may utilize mats, blocks, belts, and blankets.
- interventionNames
- Behavioral: Yoga
- type
- ACTIVE_COMPARATOR
- label
- Stretching and Toning
- description
- This 12 week, progressive stretching and toning course will aid participants in building whole body strength and flexibility by utilizing weights, chairs, mats, and various other exercise equipment. Sessions will meet three times a week for 50 minutes and will offer 'easy' and 'hard' modifications taught by an exercise leader.
- interventionNames
- Behavioral: Stretching and Toning
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 30-70 years of age * Cancer diagnosis * 1 year since last cancer treatment (surgery, chemotherapy, and/or radiation) * Not planning to receive treatment during study period * Completion of Physical Activity Readiness Questionnaire (PAR-Q) * Ambulatory and absence of health conditions that may be exacerbated by yoga, walking, or strength training * Physician consent (if deemed necessary) * Low-active, i.e. less than 150 minutes/week of moderate to vigorous exercise, no current yoga practice (including within last six months) * Intention to remain in the Champaign-Urbana area over the study duration * Willingness to be randomly assigned to one of the three groups (yoga, aerobic walking, strength training) * Comfortable with reading, writing, and speaking English Exclusion Criteria: * Below 30 or above 70 years of age * Cancer diagnosis of the brain * Less than 1 year since last treatment (surgery, chemotherapy, and/or radiation) or plans to receive treatment during study * Determined ambulatory or 'high risk' based on responses to PAR-Q * High-active (exercising more than 150 minutes/week in the last six months) * No consent from physician * Intent to be away from the Champaign-Urbana area for an extended period of time during the study * Inability to communicate effectively in English
References
Publications (2)
- DERIVEDGothe NP, Erlenbach E, Salerno EA. Yoga improves self-reported cognitive function among cancer survivors: results from the STAYFit trial. Front Cognit. 2024 May 10;3:1334727. doi: 10.3389/fcogn.2024.1334727. eCollection 2024. PMID 42339439
- DERIVEDGothe NP, Erlenbach ED, Streeter SL, Lehovec L. Effects of yoga, aerobic, and stretching and toning exercises on cognition in adult cancer survivors: protocol of the STAY Fit pilot randomized controlled trial. Trials. 2020 Sep 15;21(1):792. doi: 10.1186/s13063-020-04723-2. PMID 32933561