Clinical trial · Interventional
Exercise Program Among Lung Cancer Dyads
Pilot Study of a Progressive Exercise Program Among Lung Cancer Patient-Partner Dyads
NCT03649737CI-TRIAL-00048731PEP-LCcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pilot study of an exercise program among patients with all stages of lung cancer examining feasibility and acceptability. Preliminary outcomes include objective measures of physical function, depression, adherence to lung cancer treatments, Quality of Life (QOL), and social support.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Depression | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Lung Cancer Symptoms | — | UNRESOLVED | — |
| Pain | — | UNRESOLVED | — |
| Physical Activity | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise Intervention | Behavioral | — | UNRESOLVED |
| Quality-of-Life Assessment | Other | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Supportive care (exercise)
- description
- Participants attend supervised group exercises classes twice per week during weeks 1-6 and once per week during weeks 7-12. Participants also attend home-based unsupervised exercise sessions via an instructional DVD once per weeks over for 30 minutes during weeks 1-6 and twice per week during weeks 7-12.
- interventionNames
- Behavioral: Exercise Intervention
- Other: Survey Administration
- Other: Quality-of-Life Assessment
Primary outcomes (2)
- measure
- Study Feasibility: Proportion enrolled
- timeFrame
- 12 weeks
- description
- Will be measured as the number of couples who enroll out of those approached. Will evaluate using descriptive statistics.
- measure
- Study Acceptability: Average attendance
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Mild depression symptoms * Able to participate in exercise program per physician approval * Available partner/spouse to participate with patient Exclusion Criteria: * Persistent severe depression symptoms * Inability to participate in exercise * Life expectancy less than 1 year
References
Publications (37)
- BACKGROUNDWalker J, Holm Hansen C, Martin P, Sawhney A, Thekkumpurath P, Beale C, Symeonides S, Wall L, Murray G, Sharpe M. Prevalence of depression in adults with cancer: a systematic review. Ann Oncol. 2013 Apr;24(4):895-900. doi: 10.1093/annonc/mds575. Epub 2012 Nov 21. PMID 23175625
- BACKGROUNDSullivan DR, Ganzini L, Duckart JP, Lopez-Chavez A, Deffebach ME, Thielke SM, Slatore CG. Treatment receipt and outcomes among lung cancer patients with depression. Clin Oncol (R Coll Radiol). 2014 Jan;26(1):25-31. doi: 10.1016/j.clon.2013.09.001. Epub 2013 Sep 27. PMID 24080122
- BACKGROUNDSullivan DR, Forsberg CW, Ganzini L, Au DH, Gould MK, Provenzale D, Slatore CG. Longitudinal Changes in Depression Symptoms and Survival Among Patients With Lung Cancer: A National Cohort Assessment. J Clin Oncol. 2016 Nov 20;34(33):3984-3991. doi: 10.1200/JCO.2016.66.8459. Epub 2016 Oct 31. PMID 27996350
- BACKGROUNDMassie MJ. Prevalence of depression in patients with cancer. J Natl Cancer Inst Monogr. 2004;(32):57-71. doi: 10.1093/jncimonographs/lgh014. PMID 15263042
- BACKGROUNDLyons KS, Miller LM, McCarthy MJ. The Roles of Dyadic Appraisal and Coping in Couples With Lung Cancer. J Fam Nurs. 2016 Nov;22(4):493-514. doi: 10.1177/1074840716675976. Epub 2016 Oct 31. PMID 27803239
- BACKGROUNDBrown Johnson CG, Brodsky JL, Cataldo JK. Lung cancer stigma, anxiety, depression, and quality of life. J Psychosoc Oncol. 2014;32(1):59-73. doi: 10.1080/07347332.2013.855963. PMID 24428251
- BACKGROUNDCataldo JK, Jahan TM, Pongquan VL. Lung cancer stigma, depression, and quality of life among ever and never smokers. Eur J Oncol Nurs. 2012 Jul;16(3):264-9. doi: 10.1016/j.ejon.2011.06.008. Epub 2011 Jul 30. PMID 21803653