Clinical trial · Interventional
Effects of Scalp Nerve Block With Ropivacaine on Postoperative Recovery Quality
Effects of Preoperative Scalp Nerve Block on Postoperative Recovery Quality in Patients Undergoing Excision of Intracranial Meningioma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients undergoing elective meningeoma resection surgery will be randomly assigned to one of the following two groups. After anesthesia induction but before skull-pin insertion, one group will receive scalp nerve blocks with 0.5% ropivacaine, whereas the other group will receive scalp nerve blocks with 0.9% saline. The patients' postoperative recovery quality, which is evaluated by KPS score, peri-operative inflammatory responses, and post-operative pain degree will be evaluated and compared between the two groups.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Meningioma | Meningioma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ropivacaine | Procedure | — | UNRESOLVED |
| saline | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- ropivacaine
- description
- After anesthesia induction but before skull-pin insertion, patients in this group will receive scalp nerve blocks with 0.5% ropivacaine
- interventionNames
- Procedure: ropivacaine
- type
- PLACEBO_COMPARATOR
- label
- saline
- description
- After anesthesia induction but before skull-pin insertion, patients in this group will receive scalp nerve blocks with 0.9% saline
- interventionNames
- Procedure: saline
Primary outcomes (1)
- measure
- KPS score
- timeFrame
- 7 days post-surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. 18-75 years old; 2. BMI 18-28 kg/m2; 3. ASA Physical Status 1-2; 4. Clinical diagnosis of primary Meningeoma and will have elective Meningeoma Resection Surgery; 5. With an estimated surgery time of less than 4h; 6. The incision will be conducted at the frontal, top or the temperal skull. Exclusion Criteria: 1. A history of previous brain surgery; 2. Severe systemic disease (heart, lung, kidney, or immune system); 3. Nerval or mental disorders; 4. A history of addiction to opioids; 5. Allergic to ropivacaine; 6. Infection at block site or severe systemic infection; 7. Refuse to attend the trial.
References
Publications (0)
Data not yet available