Clinical trial · Interventional
The Comparison of Single and Multi-incision MIE for Esophageal Cancer
The Comparison of Single and Multi-incision Minimally Invasive Esophagectomy for Treating Esophageal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Minimally invasive esophagectomy (MIE) has been gradually adopted as a feasible and effective treatment option for esophageal cancer. Previously the investigators have published the adoption of single-incision approach both in the thoracoscopic and laparoscopic phases in MIE (SIMIE).The preliminary clinical results showed that SIMIE can provide an equivalent perioperative outcome whereas reduced the wound pain on the days 7 after surgery as compared to MIE performed with multi-incision (MIMIE). The goal of the current study was to conduct a prospective randomized trial to compare the perioperative outcome and survival of SIMIE and MIMIE.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Minimally invasive esophagectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- single-incision MIE
- description
- Esophageal cancer patients received single-incision Minimally invasive esophagectomy
- interventionNames
- Procedure: Minimally invasive esophagectomy
- type
- ACTIVE_COMPARATOR
- label
- multi-incision MIE
- description
- Esophageal cancer patients received multi-incision Minimally invasive esophagectomy
- interventionNames
- Procedure: Minimally invasive esophagectomy
Primary outcomes (1)
- measure
- Overall survival rate
- timeFrame
- 60 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 35 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with a diagnosis of esophageal cancer 2. Age between 35 to 75 years old 3. Resectable tumor as evaluation by preoperative imaging studies. Exclusion Criteria: 1. Previous surgery in the chest or abdomen. 2. Receiving definitive chemoradiation (5500 cGy or more). 3. Tumor invasion to the trachea, spine or aorta. 4. Liver cirrhosis with esophageal varices or liver cirrhosis refractory to medical treatment, Child C classification. 5. Previous history of cerebral vascular attack.
References
Publications (0)
Data not yet available