Clinical trial · Interventional
CBPR - BRCA Genetic Testing Among Orthodox Jews
Understanding Social, Cultural, and Religious Factors Influencing BRCA Genetic Testing in the Orthodox Jewish Community
NCT03624088CI-TRIAL-00036838completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates a web-based decision aid, named RealRisks, in promoting genetic testing intention among Orthodox Jewish women. 50 Orthodox Jewish women will take a baseline survey, self-administer the decision aid, and then complete two more surveys: one within one month of completing the decision aid and one at 6 months after completing the decision aid.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| RealRisks | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Single-Arm Intervention
- description
- Participants will complete a baseline questionnaire. They will then self-administer the web-based decision aid, RealRisks. Upon completion, they will complete two more surveys: one within 1 month of completing RealRisks and one six months after completing RealRisks.
- interventionNames
- Behavioral: RealRisks
Primary outcomes (1)
- measure
- Change in proportion of participants who intend to undergo or have completed genetic testing compared to baseline
- timeFrame
- 1 month
- description
- Question assessing subject's intention of undergoing genetic testing or completion of genetic testing
Secondary outcomes (1)
- measure
- Change in proportion of participants who make an informed choice about getting BRCA genetic testing.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 25 Years
Show eligibility criteria text
Inclusion Criteria: * \>= 25 years of age * Completed a previous cross-sectional survey and agreed to future contact * Eligible for BRCA testing based on Six Point Scale Exclusion Criteria: * Personal history of breast or ovarian cancer * Prior genetic counseling or genetic testing for BRCA mutations * Participated in previous RealRisks workshop
References
Publications (1)
- DERIVEDTrivedi MS, Manley H, Yi H, Silverman T, Chung WK, Appelbaum PS, Starck R, Schecter I, Kukafka R, Crew KD. Pilot study of a decision aid on BRCA1/2 genetic testing among Orthodox Jewish women. Fam Cancer. 2024 Nov;23(4):491-498. doi: 10.1007/s10689-024-00371-6. Epub 2024 Apr 12. PMID 38609522