Clinical trial · Observational
Prospective Pilot Study Identifying Clinically Relevant Biological Targets for Medical Therapy
Advancing Treatment for Pediatric Craniopharyngioma: Prospective Pilot Study Identifying Clinically Relevant Biological Targets for Medical Therapy
NCT03610906CI-TRIAL-00106266enrolling by invitationClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
New data suggests that the current treatment for pediatric adamantinomatous craniopharyngioma (CPA) may not be as effective as it could be.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Craniopharyngioma, Child | Craniopharyngioma | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tumor and Blood Specimens | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Pediatrics with Tumors
- description
- Pediatrics who have a tumor specimen that is suspected to be craniopharyngioma, but is deemed superfluous to the clinical care of the patient (e.g. pathological diagnosis).
- interventionNames
- Procedure: Tumor and Blood Specimens
Primary outcomes (5)
- measure
- Identification of Potential Therapeutic Targets
- timeFrame
- Beginning of study to end of study, up to 1 year.
- description
- Investigators will identify potential therapeutic targets through mRNA expression.
- measure
- Identification of Potential Therapeutic Targets
- timeFrame
- Beginning of study to end of study, up to 1 year.
- description
- Investigators will identify potential therapeutic targets through microarray analysis.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Days
- Maximum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients between 0-21 years of age. 2. Patients with the diagnosis or clinical suspicion of craniopharyngioma in whom planned clinical management will include tissue sampling. Exclusion Criteria: 1. Patients in whom final pathology does not demonstrate adamantinomatous craniopharyngioma 2. Patients in whom tissue specimen is not obtained/available 3. Patients over 21 years of age. 4. Patients who choose not to participate
References
Publications (0)
Data not yet available
No reference posted for this study.