Clinical trial · Interventional
Qudratus Lumborum Block for Postoperative Pain After Endoscopic Prostatectomy.
Ultrasound-guided Quadratus Lumborum Block for Postoperative Pain Control After Endoscopic Prostatectomy - Double Blinded, Placebo-controlled, Randomised Trial.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Laparoscopic prostatectomy (LP) is characterized by substantial tissue trauma, despite its minimally -invasive approach. Although postoperative pain intensity is lower when compared to open procedures, the use of opioids is common. Retrospective review of available LP cases revealed that although analgesic demand varied, nearly all of our LP patients required opioids postoperatively. Bilateral Quadratus Lumborum Block (QLB), being one of relatively new features of regional anesthesia, offers good analgesia of abdominal wall, with the potential for control of visceral pain. This study was established to evaluate its effectiveness in alleviating pain after radical prostatectomy in a double - blind, placebo - controlled manner.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 30 milliliters of 0.375% Ropivacaine | Drug | — | UNRESOLVED |
| 30 milliliters of 0.9% NaCl | Drug | — | UNRESOLVED |
| Qadratus Lumborum Block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- QLB with 0,375% ropivacaine
- interventionNames
- Procedure: Qadratus Lumborum Block
- Drug: 30 milliliters of 0.375% Ropivacaine
- type
- PLACEBO_COMPARATOR
- label
- QLB with 0,9% NaCl
- interventionNames
- Procedure: Qadratus Lumborum Block
- Drug: 30 milliliters of 0.9% NaCl
Primary outcomes (1)
- measure
- Opioid consumption following prostatectomy
- timeFrame
- 24 hours
- description
- Oxycodone consumption with Patient-Controlled Analgesia pump
Secondary outcomes (3)
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * ASA status less or equal 3 * Scheduled for transperitoneal or extraperitoneal endoscopic prostatectomy * Able to understand information provided and to sign the informed consent for participation in the study Exclusion Criteria: * known allergy to local anesthetics and opioids * infection in the area of block placement * known chronic use of opioids, gabapentinoids and tricyclic antidepressants * mental inability to understand the principles and rules of patient-controlled analgesia pump
References
Publications (0)
Data not yet available