Clinical trial · Interventional
COaching and Prehabilitation: Faisability Study in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
Feasibility Study of Tripartite Prehabilitation of Patients With Acute Myeloid Leukaemia and High-risk Myelodysplastic Syndromes During Intensive Chemotherapy Before Allogenic Haematopoietic Stem Cell Transplantation: the COHABILIT Protocol
NCT03595787CI-TRIAL-00083900COHABILITactive not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This faisability study aims to evaluate the adhesion of the patient to a multidisciplinary program (adapted physical activity, coaching and nutrition)
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Myeloid Leukemia | Acute Myeloid Leukemia | CURATED_BROADER | 0.80 |
| Myelodysplastic Syndromes | Myelodysplastic Syndrome | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Coaching and Habilitation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Prehabilitation program
- description
- Program based on nutritional support, physical activity program and coaching. Home-based monitoring will be done thanks to connected watches (step counter pedometer) and a connected body fat weight scale
- interventionNames
- Procedure: Coaching and Habilitation
Primary outcomes (1)
- measure
- feasibility to the adapted multidisciplinary program
- timeFrame
- 6 months
- description
- proportion of patients who will complete more than 50% of the APA/coaching sessions prescribed
Secondary outcomes (39)
- measure
- Evaluate change in functional capacity
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of acute myeloid leukemia or high-risk myelodysplastic syndrome * Age between 18 and 70 years * Eligible for an intensive chemotherapy * Eligible for allograft * Able to answer a questionnaire Exclusion Criteria: * Diagnosis of acute promyelocytic Leukemia * Palliative treatment * Contraindication to moderate physical activity * Performans status 4, unless it is related to the disease * Patient who does not understand French * Patient unable to use a smartphone * Patient deprived of liberty or placed under the authority of a tutor, * Patient considered socially or psychologically unable to comply with the treatment and the required medical follow-up.
References
Publications (1)
- DERIVEDSaillard C, Cuvelier S, Villaron-Goetgheluck C, Boher JM, Almeida-Lopez L, Le Corroller AG, Denis P, Rivieccio C, Calvin S, Vey N, Bannier-Braticevic C. Tripartite prehabilitation of patients with acute myeloid leukaemia and high-risk myelodysplastic syndromes during intensive chemotherapy before allogeneic haematopoietic stem cell transplantation (COHABILIT): protocol for an innovating prospective multicentre study. BMJ Open. 2024 Mar 29;14(3):e076321. doi: 10.1136/bmjopen-2023-076321. PMID 38553062