Clinical trial · Observational
Radiomics of Mp-MRI Assessing NAC Outcome in Breast Cancer
Radiomics of Multiparametric MRI for Neoadjuvant Chemotherapy Outcomes Assessment in Breast Cancer
NCT03592004CI-TRIAL-00033849unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a single-arm, multicentre study that aims to assess whether Radiomics combining multiparametric MRI and clinical data could be a good predictor of the responses to neoadjuvant chemotherapy in Breast Cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Multi-parametric MRI | — | UNRESOLVED | — |
| Neoadjuvant Chemotherapy | — | UNRESOLVED | — |
| Radiomics | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| neoadjuvant chemotherapy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (7)
- label
- Guangdong General Hospital
- interventionNames
- Other: neoadjuvant chemotherapy
- label
- Cancer Hospital Chinese Academy Of Medical Sciences
- interventionNames
- Other: neoadjuvant chemotherapy
- label
- Beijing Friendship Hospital
- interventionNames
- Other: neoadjuvant chemotherapy
- label
- Yunnan Cancer Hospital
- interventionNames
- Other: neoadjuvant chemotherapy
- label
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * biopsy-proven invasive breast cancer; * received complete neoadjuvant chemotherapy and no treatment has been done before; * surgery was performed after completion of neoadjuvant chemotherapy, after which pCR was confirmed by postoperative pathological examination; * pretreatment MRI data within a month before the start of the treatment was eligible, including T2WI, DWI and DCE-MRI. Exclusion Criteria: * not completing neoadjuvant chemoradiotherapy; * not undergoing surgery at our hospital, or pCR was not assessed; * lack of T2WI, or DWI or DCE-MRI data; * insufficient MRI quality to obtain measurements (e.g., owing to motion artifacts); * had unilateral multifocal cancers, and the correlation between the tumor in MR images and postoperative pathological examination was uncertain.
References
Publications (0)
Data not yet available
No reference posted for this study.