Clinical trial · Interventional
Comparison of the Duration of Ropivacaine Combined With Dexmedetomidine or Dexamethasone on Paravertebral Block
Comparison of the Duration of Ropivacaine Combined With Dexmedetomidine or Dexamethasone on Paravertebral Block in Patients Undergoing Video-assisted Thoracic Surgery
NCT03570645CI-TRIAL-00041808completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study was a prospective, randomized, controlled, and double-blind trial. Major assessments were made during the operation and 48 h postoperatively.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| control group | Drug | — | UNRESOLVED |
| dexamethasone group | Drug | — | UNRESOLVED |
| Dexmedetomidine Group | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- dexmedetomidine group
- description
- thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine 100 ug every time
- interventionNames
- Drug: Dexmedetomidine Group
- type
- EXPERIMENTAL
- label
- dexamethasone Group
- description
- thoracic paravertebral blocks using a combination of ropivacaine and dexamethasone 10 mg every time
- interventionNames
- Drug: dexamethasone group
- type
- SHAM_COMPARATOR
- label
- control group
- description
- thoracic paravertebral blocks using only ropivacaine
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * (1) age 18 to 65 years, * (2) scheduled to undergo video-assisted thoracic surgery, * (3) American Society of Anesthesiologists risk classification I-II. Exclusion Criteria: * (1) patient refusal; * (2) known hypersensitivity to the study medication (ropivacaine); * (3) long-term use of opioids; * (4) liver or renal insufficiency; * (5) a history of psychiatric or neurological disease; * (6) deafness; * (7) regular use of acetaminophen, nonsteroidal anti-inflammatory drugs, corticosteroids, or antiemetics; and * (8) a preoperative Pittsburgh Sleep Quality Index (PSQI) global score higher than 6.
References
Publications (0)
Data not yet available
No reference posted for this study.