Clinical trial · Interventional
African American Families Fighting Parental Cancer Together
NCT03567330CI-TRIAL-00082924terminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Insufficient patients meet eligibility requirements.
Summary
Brief summary (as posted)
The purpose of this study is to test the usefulness of a family-based program for African American parents/primary caregivers with newly diagnosed solid tumor cancer and their adolescent children. The program is designed to promote family communication reduce and depressive symptoms for adolescence.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Depressive Symptoms | — | UNRESOLVED | — |
| Parental Stress | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Family-based attachment-focused intervention | Behavioral | — | UNRESOLVED |
| Psychoeducation | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Experimental
- description
- Family-based attachment-focused intervention for families where parent/caregiver is within 12 months of first diagnosis of a stage I-III solid tumor cancer.
- interventionNames
- Behavioral: Family-based attachment-focused intervention
- type
- ACTIVE_COMPARATOR
- label
- Psychoeducation
- description
- Provides equivalent number of American Cancer Society psychoeducational sessions.
- interventionNames
- Behavioral: Psychoeducation
Primary outcomes (1)
- measure
- Reduce 8-week depressive symptoms among African American adolescents on the Child Depression Inventory (CDI-2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 11 Years
Show eligibility criteria text
Inclusion Criteria: * Parents must identify as non-Hispanic Black * Must be diagnosed for the first time with stage 0, I, II, or III solid tumor cancer (e.g., breast, prostate, colorectal, lung) or hematologic cancer in the last 24 months * Must be parent or primary caregiver of at least 1 adolescent living (target child) at home (ages 11-21) who has been told about the diagnosis Exclusion Criteria: * Parents with serious mental health illness that prevents them from participating in the group sessions (e.g., clinically relevant depressive symptomatology as evidenced by the Center for Epidemiological Studies Depression Scale \>27) * Parents with psychotic features or severe cognitive impairment * Parents not fluent in English. * Severely depressed adolescents (CDI-2; T-scores of 70 and higher on the total 28-item CDI-2 scale * Severely anxious adolescents (RCMAS-2; We will use a cutoff score of 71 (T-score) or higher to screen out African American adolescents with severe anxiety) at baseline * Adolescents with psychotic features * Adolescents with cognitive impairment (e.g., mental retardation, severe developmental disorders) as evidenced by educational records, parental report and/or clinical impression * Adolescents currently in active outpatient mental health treatment.
References
Publications (1)
- RESULTMcKinney NS, Virtue S, Lewis FM, Willis AI, Pettyjohn T, Harmon LR, Davey A. Study protocol: a randomized control trial of African American families fighting parental cancer together. BMC Cancer. 2018 Nov 20;18(1):1140. doi: 10.1186/s12885-018-5052-8. PMID 30453906