Clinical trial · Interventional
The Breast Cancer & Physical Activity Level (BC-PAL) Pilot Study
NCT03564899CI-TRIAL-00049370BC-PALcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Breast Cancer \& Physical Activity Level (BC-PAL) pilot study is a randomized controlled pilot trial aimed at evaluating whether total physical activity levels, health-related fitness and patient reported outcomes are improved by promoting different intensities of physical activity participation within a home-based setting, and whether these improvements are maintained over the long-term, in inactive breast cancer survivors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Survivorship | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Higher intensity physical activity intervention | Behavioral | — | UNRESOLVED |
| Lighter intensity physical activity intervention | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- control
- description
- Receive no physical activity intervention (maintain baseline physical activity participation)
- type
- EXPERIMENTAL
- label
- Lighter intensity physical activity
- description
- Receive an intervention of 300 minutes/week of physical activity at an intensity of 40-60% of heart rate reserve for 12 weeks.
- interventionNames
- Behavioral: Lighter intensity physical activity intervention
- type
- ACTIVE_COMPARATOR
- label
- Higher intensity physical activity
- description
- Receive an intervention of 150 minutes/week of physical activity at an intensity of 60-80% of heart rate reserve for 12 weeks.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically-confirmed Stage I-III breast cancer diagnosis * Completion of adjuvant treatment (chemotherapy, radiation therapy and surgery) except for hormone therapy * Females ≥18 years of age * Currently living in the Calgary area and able to meet with study staff at the Holy Cross Center on at least six occasions (twice as baseline, 12- and 24-weeks) * Currently inactive (accumulating ≤ 60 minutes of moderate-vigorous intensity physical activity/week and ≤ 10,000 steps/day) * Ability to undertake a physical activity program \[assessed by an Exercise Physiologist with the Physical Activity Readiness Questionnaire (PAR-Q+)\]. Exclusion Criteria: * Deemed too active (accumulating on average ≥ 60 minutes of moderate-vigorous intensity physical activity/week and ≥ 10,000 steps/day) * Being away from Calgary or not able to attend testing sessions/be contacted by study staff for \> 4 consecutive weeks during the intervention period.
References
Publications (2)
- DERIVEDMcNeil J, Fahim M, Stone CR, O'Reilly R, Courneya KS, Friedenreich CM. Adherence to a lower versus higher intensity physical activity intervention in the Breast Cancer & Physical Activity Level (BC-PAL) Trial. J Cancer Surviv. 2022 Apr;16(2):353-365. doi: 10.1007/s11764-021-01030-w. Epub 2021 Mar 22. PMID 33754246
- DERIVEDMcNeil J, Brenner DR, Stone CR, O'Reilly R, Ruan Y, Vallance JK, Courneya KS, Thorpe KE, Klein DJ, Friedenreich CM. Activity Tracker to Prescribe Various Exercise Intensities in Breast Cancer Survivors. Med Sci Sports Exerc. 2019 May;51(5):930-940. doi: 10.1249/MSS.0000000000001890. PMID 30694978