Clinical trial · Interventional
Endocuff Vision Colonoscopy vs. AmplifEYE Colonoscopy
Comparison of Endocuff Vision to Medivators AmplifEYE for Detection of Precancerous Colorectal Polyps.
NCT03560128CI-TRIAL-00041037completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aims to compare the results between colonoscopies with two different attachments on the distal end of the colonoscope.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Adenoma | Colorectal Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Colorectal Polyp | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| AmplifEYE device | Device | — | UNRESOLVED |
| Endocuff Vision device | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Endocuff Vision Arm
- description
- Colonoscopy with Endocuff Vision device attached to the distal end of the scope.
- interventionNames
- Device: Endocuff Vision device
- type
- EXPERIMENTAL
- label
- AmplifEYE Arm
- description
- Colonoscopy with AmplifEYE device attached to the distal end of the scope.
- interventionNames
- Device: AmplifEYE device
Primary outcomes (1)
- measure
- Number of Adenomas Detected Per Colonoscopy (APC).
- timeFrame
- During colonoscopy procedure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * 40 years of age or older * Undergoing colonoscopy for screening, surveillance, or diagnostic purposes * Able to provide written informed consent Exclusion Criteria: * Active Inflammatory Bowel Disease * Prior resection of the colon * Referred for resection of a polyp identified by another physician * Referred for a previous incomplete colonoscopy
References
Publications (2)
- BACKGROUNDRex DK, Repici A, Gross SA, Hassan C, Ponugoti PL, Garcia JR, Broadley HM, Thygesen JC, Sullivan AW, Tippins WW, Main SA, Eckert GJ, Vemulapalli KC. High-definition colonoscopy versus Endocuff versus EndoRings versus full-spectrum endoscopy for adenoma detection at colonoscopy: a multicenter randomized trial. Gastrointest Endosc. 2018 Aug;88(2):335-344.e2. doi: 10.1016/j.gie.2018.02.043. Epub 2018 Mar 9. PMID 29530353
- DERIVEDRex DK, Sagi SV, Kessler WR, Rogers NA, Fischer M, Bohm ME, Dewitt JM, Lahr RE, Searight MP, Sullivan AW, McWhinney CD, Garcia JR, Broadley HM, Vemulapalli KC. A comparison of 2 distal attachment mucosal exposure devices: a noninferiority randomized controlled trial. Gastrointest Endosc. 2019 Nov;90(5):835-840.e1. doi: 10.1016/j.gie.2019.06.046. Epub 2019 Jul 15. PMID 31319060