Clinical trial · Observational
3D-CT-guided Percutaneous Radiofrequency Thermocoagulation for Tumor-related Trigeminal Neuralgia
The Long-Term Outcome of 3D-CT-guided Percutaneous Radiofrequency Thermocoagulation for Tumor-related Trigeminal Neuralgia: A Retrospective Study.
NCT03549013CI-TRIAL-00033238completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to investigate the effectiveness and safety of 3D-CT-guided percutaneous radiofrequency thermocoagulation for the treatment of tumor-related trigeminal neuralgia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Trigeminal Neuralgia, Secondary | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Cumulative recurrence-free rate
- timeFrame
- The enrollment of our study began on March 1st 2007 and ended on 31st October 2017. All following-up has been finished before February 28th 2018.
- description
- The modified Barrow Neurological Institute (BNI) pain intensity score will be used to assess pain degree. Pain relief degree will be evaluated as BNI I= no pain without medication, BNI II= occasional pain, not require medication, BNI IIIa= no pain with medication, BNI IIIb= Controlled pain with medication, BNI IV= improved pain that inadequately controlled by medication, BNI IV= persistent pain that inadequately controlled by medication. A BNI grade that increased to IV-V from I-IIIb after operation was defined as recurrence.
Secondary outcomes (2)
- measure
- Patient satisfaction
- timeFrame
- From pre-operation to 1 week after operation
- description
- Patient satisfaction is evaluated by a 5-point Likert scale, while 1 point represents very unsatisfactory and 5 points indicates very satisfactory
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * age\>18 years, * typical TN symptoms in the same lateral as intracranial tumors, * uncontrolled symptoms or intolerable side effects of medication, * pain duration longer than 90 days * brain magnetic resonance imaging (MRI)confirmed that the trigeminal pain was secondary to intracranial tumors. Exclusion Criteria: * patients with infection at the puncture site, * coagulopathy, * epilepsy, * other causes of TN, * a history of mental disorders or anesthetic drug abuse.
References
Publications (9)
- BACKGROUNDKim SK, Kim DG, Se YB, Kim JW, Kim YH, Chung HT, Paek SH. Gamma Knife surgery for tumor-related trigeminal neuralgia: targeting both the tumor and the trigeminal root exit zone in a single session. J Neurosurg. 2016 Oct;125(4):838-844. doi: 10.3171/2015.7.JNS15451. Epub 2016 Jan 22. PMID 26799302
- BACKGROUNDCho KR, Lee MH, Im YS, Kong DS, Seol HJ, Nam DH, Lee JI. Gamma knife radiosurgery for trigeminal neuralgia secondary to benign lesions. Headache. 2016 May;56(5):883-889. doi: 10.1111/head.12801. Epub 2016 Apr 4. PMID 27041354
- BACKGROUNDFurtado SV, Hegde AS. Trigeminal Neuralgia Due to a Small Meckel's Cave Epidermoid Tumor: Surgery Using an Extradural Corridor. Skull Base. 2009 Sep;19(5):353-7. doi: 10.1055/s-0029-1220201. PMID 20190946
- BACKGROUNDCheng TM, Cascino TL, Onofrio BM. Comprehensive study of diagnosis and treatment of trigeminal neuralgia secondary to tumors. Neurology. 1993 Nov;43(11):2298-302. doi: 10.1212/wnl.43.11.2298. PMID 8232946
- BACKGROUNDKhan N, Michael A, Choucair A, Bit-Ivan E. Trigeminal Ganglioneuroma: A Rare Case of Trigeminal Neuralgia Caused by Cerebellopontine Angle Tumor. World Neurosurg. 2017 Mar;99:811.e7-811.e10. doi: 10.1016/j.wneu.2016.12.085. Epub 2016 Dec 30. PMID 28043883
- BACKGROUNDKobata H, Kondo A, Iwasaki K. Cerebellopontine angle epidermoids presenting with cranial nerve hyperactive dysfunction: pathogenesis and long-term surgical results in 30 patients. Neurosurgery. 2002 Feb;50(2):276-85; discussion 285-6. doi: 10.1097/00006123-200202000-00008. PMID 11844262
- BACKGROUNDKanpolat Y, Savas A, Bekar A, Berk C. Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1,600 patients. Neurosurgery. 2001 Mar;48(3):524-32; discussion 532-4. doi: 10.1097/00006123-200103000-00013.