Clinical trial · Interventional
Auricular Acupressure (AA) For Insulin Resistance in Women With Polycystic Ovary Syndrome
Effect of Auricular Points Acupressure for Overweight/Obese Women With Polycystic Ovary Syndrome.
NCT03546595CI-TRIAL-00042472unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The present trial is a pilot study to investigate the effect of auricular acupressure on insulin resistance in women with PCOS.A total of 100 subjects will be enrolled into this study and will be randomized into two groups. Auricular acupressure or sham auricular acupressure will be treated for three months. The primary outcome is the whole body insulin action assessed with HOMA-IR.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Insulin Resistance | — | UNRESOLVED | — |
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Auricular acupoints acupressure | Other | — | UNRESOLVED |
| Sham auricular acupoints acupressure | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Auricular acupoints acupressure
- interventionNames
- Other: Auricular acupoints acupressure
- type
- SHAM_COMPARATOR
- label
- Sham auricular acupoints acupressure
- interventionNames
- Other: Sham auricular acupoints acupressure
Primary outcomes (1)
- measure
- Homeostasis model assessment-insulin resistance (HOMA-IR)
- timeFrame
- 3 month
- description
- HOMA-IR was calculated as \[Plasma glucose (GLU,mmol/L)\* serum insulin (mIU/L)\] / 22.5.
Secondary outcomes (15)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 15 Years
- Maximum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Women aged between 15 and 40 years. * Diagnosis of PCOS according to the modified Rotterdam criteria. * 2 years after menarche. * Body mass index (BMI) equal to or greater than 23 kg/m2. * IR is defined by the homeostaticmodel assessment (HOMA-IR: (fasting insulin (μU/mL)×fasting glucose (mmol/L))/22.5). A value ≥2.14 will be considered to be indicative of IR. * With no desire of children within 3 months. Exclusion Criteria: * Administration of other medications known to affect reproductive function or metabolism within the past three months, including oral contraceptives, Gonadotropin-releasing hormone (GnRH) agonists and antagonists, anti androgens, gonadotropins, anti-obesity drugs, Chinese herbal medicines, anti diabetic drugs such as metformin and thiazolidinediones, somatostatin, diazoxide, and calcium channel blockers. * Patients with other endocrine disorders including 21-hydroxylase deficiency, hyperprolactinemia, uncorrected thyroid disease, suspected Cushing's syndrome. * Patients with known severe organ dysfunction or mental illness.
References
Publications (1)
- DERIVEDLi Y, Hou L, Wang Y, Xie L, Zhang M, Pan Z, Li Y, Ding Y, Sun M, Qu Y, Liu S. Auricular points acupressure for insulin resistance in overweight/obese women with polycystic ovary syndrome: protocol for a randomised controlled pilot trial. BMJ Open. 2019 May 28;9(5):e027498. doi: 10.1136/bmjopen-2018-027498. PMID 31142530