Clinical trial · Interventional
Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors
NCT03539835CI-TRIAL-00046201completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will begin to fill a knowledge gap by determine whether changes in kynurenine metabolism occur following Resistance Training (RT) and relate to reductions in inflammation and improved behavioral and physical function as this may identify potential targets for interventions to promote cancer recovery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cognitively-based compassion training control (CBCT) | Behavioral | — | UNRESOLVED |
| Resistance training (RT) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Resistance training
- interventionNames
- Other: Resistance training (RT)
- type
- ACTIVE_COMPARATOR
- label
- Cognitively-based compassion training
- interventionNames
- Behavioral: Cognitively-based compassion training control (CBCT)
Primary outcomes (1)
- measure
- Change in fatigue assessed by Multidimensional Fatigue Inventory (MFI) score
- timeFrame
- Baseline, 12 weeks follow up
- description
- The Multidimensional Fatigue Inventory (MFI) is a 20-item self-report instrument designed to measure fatigue. It covers the following dimensions: General Fatigue, Physical Fatigue, Mental Fatigue, Reduced Motivation and Reduced Activity. Each scale contains four items for which the person had to indicate on a seven-point scale to what extent the particular statement applies to him or her. An equal number of items is worded in a positive and in a negative direction to counteract response tendencies.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 50 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. within 6 months to 10 years post active breast cancer therapy (i.e. surgery/chemotherapy) for stage I-III invasive breast cancer, 2. at least 6 months post breast reconstruction (if applicable), 3. lack of menses for at least one year, 4. BMI 20-35 kg/m2, 5. fatigued (subjective reporting ≥3 on a 1-10 scale), 6. untrained with regard to structured resistance training (no more than 3x/week). Exclusion Criteria: 1. plans for surgery (e.g., breast reconstruction) during the study period, 2. taking an anticoagulant medication (i.e. heparin, apixaban, rivaroxaban), 3. allergic to lidocaine, 4. orthopedic or chronic pain condition restricting exercise, 5. Mini-Mental Status Examination (MMSE) scores below education-specific cut-points (less than 23 for more than 9th grade education and less than 17 for less than 8th grade education), 6. unable to receive physician medical clearance.
References
Publications (0)
Data not yet available
No reference posted for this study.