Clinical trial · Observational
Lactate Levels Correlates With Ki-67 in Brain Tumor Surgery
Lactate Levels at Beginning of Surgery Correlates With Ki-67 Labeling Index in Brain Tumors
NCT03531307CI-TRIAL-00037098completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In neurosurgery, brain tumor patients show increased levels of lactate at the beginning of surgery. This has been related to malignancy. Ki-67 is a cell proliferation index used as a marker of tumor mitotic activity. This research aims to describe the correlation between lactate levels and the Ki-67 index in patients with brain tumor.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia | — | UNRESOLVED | — |
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Data correlation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Lactate and Ki 67 levels
- description
- Neurosurgical patients between June 2017 and February 2018 for tumoral and non-tumoral craniectomy with lactate levels at the beginning of surgery and Ki-67 index in biopsies.
- interventionNames
- Other: Data correlation
Primary outcomes (1)
- measure
- Evaluate the correlation between Lactate levels and Ki-67 Index
- timeFrame
- Within 1 week after data acquisition
- description
- Levels of lactate in first blood analysis after anesthesia induction and proliferation index in biopsy results
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Neurosurgical craniectomy cases * June 2017 - February 2018 * Valid lactate information after anesthesia induction * Ki-67 label index informed in biopsies * Tumor type information confirmed in biopsies Exclusion Criteria: * Incomplete lactate or Ki-67 index information
References
Publications (0)
Data not yet available
No reference posted for this study.