Clinical trial · Interventional
Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice
Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice of Extrahepatic Bile Duct: A Multi-center, Prospective, Open-labeled, Real World Study Based on Electronic Data Capture System
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the safety and effectiveness of different methods of preoperative biliary drainage in patients with extrahepatic bile duct neoplasms with obstructive jaundice (hilar cholangiocarcinoma, distal bile duct cancer, and periampullary carcinoma), including PTBD (Percutaneous Transhepatic Biliary Drainage), ENBD (Endoscopic Nasobiliary Drainage) and EBS (Endoscopic Biliary Stenting).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Jaundice, Obstructive | — | UNRESOLVED | — |
| Klatskin Tumor | Hilar Cholangiocarcinoma | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EBS group | Procedure | — | UNRESOLVED |
| ENBD group | Procedure | — | UNRESOLVED |
| PTBD group | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- PTBD group
- description
- Percutaneous Transhepatic Biliary Drainage
- interventionNames
- Procedure: PTBD group
- type
- EXPERIMENTAL
- label
- ENBD group
- description
- Endoscopic Nasobiliary Biliary Drainage
- interventionNames
- Procedure: ENBD group
- type
- EXPERIMENTAL
- label
- EBS group
- description
- Endoscopic Biliary Stenting
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who meet the following four criteria are included into the study: 1. Preoperative clinical diagnosis of hilar cholangiocarcinoma, distal bile duct cancer, periampullary cancer without distant metastasis or peripheral vascular invasion, and plan for radical surgery; 2. Serum total bilirubin is higher than 51 umol/l; 3. Age is older than 18 and younger than 80 years old; 4. Sign in informed consent to receive preoperative PTBD, ENBD, EBS or without PBD. Exclusion Criteria: * If any of the following items are met, the subject cannot enter the study. 1. Incorporate severe mental illness, severe heart, lungs and kidneys disease, etc., and be unable to tolerate surgery; 2. Malignant obstructive jaundice caused by metastatic tumors; 3. Pregnancy or lactation women.
References
Publications (0)
Data not yet available