Clinical trial · Observational
Right Ventricular Inflammation After Lung Resection
Cardiac Magnetic Resonance Assessment of Right Ventricular Inflammation After Lung Resection - a Feasibility Study
NCT03523611CI-TRIAL-00033099unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is explore the impact of lung cancer surgery on inflammation and function of the right side of the heart.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Ventricular Failure | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Lung Resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- lung resection
- description
- Patients with suspected lung cancer undergoing lung resection by anatomic lobectomy
- interventionNames
- Procedure: Lung Resection
Primary outcomes (1)
- measure
- Can RV inflammation be assessed by T1 mapping CMR following lung resection by assessing the number of CMR studies which have an IQS>1?
- timeFrame
- 2 months
- description
- The investigators will test and report inter- and intra-observer reproducibility of Region of Interest (ROI) definition in all datasets where Image Quality Score (IQS)\>1. The primary endpoint will be the number of MRI studies which have an IQS \>1.
Secondary outcomes (3)
- measure
- Are T1 values at the ventricular insertion points increased following lung resection?
- timeFrame
- 2 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria: 1. Provision of informed consent 2. Age \>16 years 3. Planned elective lung resection by VATS or open lobectomy Exclusion Criteria: 1. Pregnancy 2. On-going participation in any investigational research which could undermine the scientific basis of the study 3. Wedge, segmental or sub-lobar lung resection 4. Pneumonectomy 5. Isolated right middle lobectomy 6. Atrial fibrillation at baseline 7. Contraindication to cardiac magnetic resonance imaging 1. Cardiac pacemaker, artificial heart valve, neurostimulator, cochlear implant 2. Aneurysm clips 3. Metal injuries to the eye 4. Loose metal in a part of the body 8. Contraindication to IV Gadolinium (contrast) administration: 1. Acute or chronic renal failure 2. Allergy to contrast
References
Publications (0)
Data not yet available
No reference posted for this study.