Clinical trial · Interventional
Overnight Fasting After Completion of Therapy: The OnFACT Study
NCT03523377CI-TRIAL-00116448active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to test whether regularly not eating for at least 14 hours overnight ("intermittent fasting") is feasible and can improve blood sugar.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Cancer Survivors | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| prolonged overnight fasting | Other | — | UNRESOLVED |
| usual care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- prolonged overnight fasting
- description
- Participants randomized to the fasting arm will be instructed on how to use the SMS texting app to indicate the beginning and end of the nightly fast. In the first 2-4 weeks following the first overnight fast, intervention participants will complete three phone calls with study staff trained in motivational interviewing. These calls will be used to reinforce the prolonged overnight fasting instructions, identify barriers to prolonged overnight fasting, and support successes where they have occurred.
- interventionNames
- Other: prolonged overnight fasting
- type
- ACTIVE_COMPARATOR
- label
- usual care
- description
- Participants randomized to the usual care arm will be instructed to eat a heart-healthy diet and exercise for at least 30 minutes five days a week, which is usual counseling in our clinics.
- interventionNames
- Other: usual care
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Body mass index is ≥ 18.5 kg/m\^2 * History of treatment for cancer or related illness diagnosed at ≤ 25 years old * Off cytotoxic therapy for primary cancer ≥ 2 years * Not receiving cytotoxic therapy (chemotherapy, external beam radiation therapy) at the time of study enrollment * History of radiation to the chest, abdomen or total body * Current age ≥18 years * English-speaking * Personal phone with SMS text messaging capability * Willingness to wear an mHealth device, such as a FitBit, for two 7-day periods * Able to perform all study requirements Exclusion Criteria: * Use of any antidiabetic, weight loss, or appetite control medication * Use of any other medication that could impact dietary intake, such as prednisone * Currently fasts 12 hours or more by self-report * Unable to fast due to medical reason such as pregnancy
References
Publications (0)
Data not yet available
No reference posted for this study.