Clinical trial · Interventional
Pain and Quality of Life After Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS
Postoperative Pain and Quality of Life for Patients Undergoing Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS：A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Thoracoscopic assisted mediastinal thymectomy is currently one of the most commonly used surgical methods, but there are some deficiencies.Minimally invasive surgery through the subxiphoid approach can achieve a good surgical field of vision. (1) The surgical field is fully exposed. (2) damage to intercostal nerves can be avoided.(3) Operation time, intraoperative blood loss, postoperative Extubation time is similar to VATS. But there is still lack of evidence. In this study, 50 patients undergoing subxiphoid uniportal VATS and 50 patients undergoing intercostal uniportal VATS were included to evaluate the post-operative pain and quality of life after surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mediastinal Neoplasms | Mediastinal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Thoracic Neoplasm | Thoracic Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Thoracic Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intercostal uniportal VATS | Procedure | — | UNRESOLVED |
| Subxiphoid uniportal VATS | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Subxiphoid uniportal VATS
- description
- Standard Subxiphoid single-port video assisted mediastinal thymectomy, no use of rib-spreader.
- interventionNames
- Procedure: Subxiphoid uniportal VATS
- type
- ACTIVE_COMPARATOR
- label
- Intercostal uniportal VATS
- description
- Standard Intercostal single-port video assisted mediastinal thymectomy, no use of rib-spreader.
- interventionNames
- Procedure: Intercostal uniportal VATS
Primary outcomes (1)
- measure
- Postoperative pain
- timeFrame
- 6 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Clinical diagnosis of anterial and middle mediastinal tumors ; 2. Normal heart function, pulmonary function FEV1 %\> 60% PaO2\> 80 mmHg 3. BMI\<30 Exclusion Criteria: 1. enlargement of lymph nodes was seen in the clinical CT readings. 2. Preoperative chronic pain or chronic opioid analgesics 3. Preoperative check for mental disorders such as hyper-anxiety 4. History of previous thoracic surgery 5. Patients with thoracic deformity (eg, funnel chest and chicken breast) 6. Poor education can not understand postoperative follow-up requirements and assessment scale
References
Publications (0)
Data not yet available