Clinical trial · Interventional
Trial of Identifying the Lung Intersegmental Plane by Iron Sucrose Injection Staining
This is a Phase II Study on the Safety and Feasibility of Identifying the Intersegmental Plane of the Lung by Iron Sucrose Injection Staining,Both on the Pleural Surface and Lung Parenchyma
NCT03516500CI-TRIAL-00053589completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a protocol to determine the safety and feasibility of using Iron Sucrose Injection to identify the intersegmental plane,not only on the pleural surface but also the parenchyma of the lung.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Neoplasm | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Segmentectomy;Intersegmental Plane | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Iron Sucrose Injection | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Iron Sucrose injection group
- description
- The investigators inject Iron Sucrose (100 mg dissolved in 50 mL saline) through a butterfly needle into the bronchus of the targeting segment.
- interventionNames
- Drug: Iron Sucrose Injection
Primary outcomes (1)
- measure
- Incidence of treatment-related grade 3-5 adverse events
- timeFrame
- Up to 90 days post-surgery
- description
- Incidence of treatment-related grade 3-5 adverse events assessed using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version (v)4.0
Secondary outcomes (1)
- measure
- Surgical margin
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years ≤age ≤80 years * The patient must be scheduled to undergo segmentectomy or combined subsegmentectomy. * The patient must be willing and able to comply with all study requirements and have understood and signed the informed consent. Exclusion Criteria: * A known allergy to Iron Sucrose Injection * The patients who have Iron overdose or iron utilization barrier Intra-operative founding of extensive pigmentation Silicosis or extensive carbon deposition in the lung. * Patients who have not received segmental resection. * Patients who converted to thoracotomy.
References
Publications (1)
- DERIVEDLi C, Zhang X, Feng X, Han D, Xiang J, Li H. A feasible technique for distinguishing the intersegmental plane by transbronchial injection of iron sucrose. JTCVS Tech. 2023 Jan 16;18:137-142. doi: 10.1016/j.xjtc.2022.12.007. eCollection 2023 Apr. PMID 37096093