Clinical trial · Interventional
Fish Oil and EPO in Breast Cancer
Fish Oil and Evening Primrose Oil in the Treatment of Breast Cancer
NCT03516253CI-TRIAL-00061919unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Recent literature data suggest beneficial effects of dietary fats in patients with cancers, in particular polyunsaturated fatty acids (PUFAs). Fish oil and evening primrose oil provide a high amount of PUFAs and a desirable n-6/n-3 PUFAs ratio.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fish oil + EPO | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention group
- description
- Dietary Supplement: Fish oil + EPO. Fish oil (2 gel capsules, each 1g fish oil with 500 mg EPA+DHA) and EPO (Evening primrose oil 3 gel capsules with 117 mg GLA), 3 months with lunch.
- interventionNames
- Dietary Supplement: Fish oil + EPO
- type
- NO_INTERVENTION
- label
- Control group
- description
- Dietary Supplement: Mineral oil (5 gel capsules, each 1g mineral oil), 3 months with lunch.
Primary outcomes (2)
- measure
- Change in disease status
- timeFrame
- Baseline, 3 months, 1 year
- description
- Remission, stable disease or progression
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 45 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically confirmed breast cancer, * Clinical Stadium III and IV, * Patients able to understand requirements of the study and provide written informed consent- Exclusion Criteria: * Previous radio- or chemotherapy * Other serious chronic diseases * Statin therapy * Use of fat-based dietary supplements (such as fish oil, evening primrose oil etc) 3 months prior to study
References
Publications (1)
- DERIVEDArsic A, Krstic P, Paunovic M, Nedovic J, Jakovljevic V, Vucic V. Anti-inflammatory effect of combining fish oil and evening primrose oil supplementation on breast cancer patients undergoing chemotherapy: a randomized placebo-controlled trial. Sci Rep. 2023 Apr 20;13(1):6449. doi: 10.1038/s41598-023-28411-8. PMID 37081029