Clinical trial · Interventional
Effects of Anesthesia on Immunity in Cancer
Immunomodulatory Effects of Volatile and Total Intravenous Anesthesia for Patients With Renal Cancer
NCT03514550CI-TRIAL-00038895completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the study is a comparative study of the cellular immunity response of patients operated on for kidney cancer under total intravenous and inhalational anesthesia.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cancer | Kidney Neoplasm | PROBABILISTIC | 0.70 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Epidural block | Procedure | — | UNRESOLVED |
| Propofol | Drug | — | UNRESOLVED |
| Sevoflurane | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- total intravenous anesthesia
- description
- Patients, scheduled for nephrectomy for kidney cancer will receive neuraxial epidural block and propofol for perioperative anesthesia
- interventionNames
- Drug: Propofol
- Procedure: Epidural block
- type
- ACTIVE_COMPARATOR
- label
- Volatile anesthesia
- description
- Patients, scheduled for nephrectomy for kidney cancer will receive neuraxial epidural block and sevoflurane for perioperative anesthesia
- interventionNames
- Drug: Sevoflurane
- Procedure: Epidural block
Primary outcomes (1)
- measure
- CD 16
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Surgery for renal cancer * Signed informed concent Exclusion Criteria: * Propofol or sevoflurane intolerance * Contraindications for epidural anesthesia * Renal failure * Hepatic failure * Congestive heart failure * Previous hemotherapy * Hematological diseases
References
Publications (0)
Data not yet available
No reference posted for this study.