Clinical trial · Observational
EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice
Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-Pancreatic Malignancies: A Multicenter Prospective Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objective of the study is to evaluate the size of the common bile duct (CBD) in a large cohort of patients with jaundice secondary to pancreatic head or distal bile duct malignancy undergoing diagnostic EUS for tissue acquisition or evaluation of resectability and to establish factors associated with a dilation of the CBD greater than 15mm.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ampulla of Vater Cancer | Malignant Ampulla of Vater Neoplasm | CURATED_BROADER | 0.80 |
| Cholangiocarcinoma of the Extrahepatic Bile Duct | — | UNRESOLVED | — |
| Jaundice, Obstructive | — | UNRESOLVED | — |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic ultrasound | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Common bile duct diameter
- timeFrame
- Enrollment over 6 months
- description
- Measurement by endoscopic ultrasound in patients with malignant obstructive jaundice
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with jaundice and a pancreatic head mass lesion referred for EUS-guided tissue acquisition or staging * Patients with jaundice and a distal CBD lesion suggestive of cholangiocarcinoma or a carcinoma of the ampulla of Vater referred for EUS-guided tissue acquisition or staging * Serum bilirubin level ≥3 mg/dL * Age ≥18 years * Written informed consent Exclusion Criteria: * Presence of altered anatomy from previous gastric surgery (Billroth II or Roux-en-Y anastomosis) * Previously performed sphincterotomy, biliary plastic stent or metal stent placement * Previous percutaneous drainage of the bile duct * Pregnancy * Inability to sign the informed consent
References
Publications (0)
Data not yet available