Clinical trial · Interventional
Microwave Ablation in Ground Glass Nodules
NCT03490890CI-TRIAL-00032411unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
GGO was commonly observed recently.Radiofrequency ablation has been widely applied in the treatment of patients with GGO. No study had explored the microwave ablation in the treatment of GGO.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Microwave Ablation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Microwave ablaton | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Microwave ablation in the GGO
- description
- Patients with GGO were treated with microwave ablation.
- interventionNames
- Other: Microwave ablaton
Primary outcomes (1)
- measure
- The survival of patients with GGO treated with MWA
- timeFrame
- From the date of randomization until the date of the date of death from any cause, assessed up to 60 months
- description
- The overall survival
Secondary outcomes (1)
- measure
- The disease free survival of patients with GGO treated with MWA
- timeFrame
- From date of randomization until the date of first documented progression, assessed up to 60 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patient has a histologically verified AIS or MIA. 2. The tumors small enough to treat (usually ≤3 cm), and without chest pleura invasion. 3. Solid cements in the GGO less than 50%. 4. No other sites of disease observed. 5. Patient is not a candidate for surgical removal of the cancer, or refused surgery. 6. Patient is not a candidate for radiation therapy, or refused radiation therapy. 7. Patient has \> 6 month life expectancy. 8. Eastern Cooperative Oncology Group performance status of 0 to 2. 9. No prior anticancer treatments including surgery, radiation,chemotherapy or local treatments. 10. Sufficient organ functions. 11. Written informed consent. Exclusion Criteria: 1. Active bacterial or fungous infection. 2. Simultaneous or metachronous (within the past 5 years) double cancers. 3. Women during pregnancy or breast-feeding. 4. Interstitial pneumonitis, pulmonary fibrosis, or severe pulmonary emphysema. 5. Uncontrollable diabetes mellitus. History of severe heart disease, heart failure, myocardial infarction within the past 6 months or attack of angina pectoris within the past 6 months.
References
Publications (0)
Data not yet available
No reference posted for this study.