Clinical trial · Interventional
Disposition of Dietary Polyphenols and Methylxanthines in Mammary Tissues From Breast Cancer Patients
Metabolic Profiling of Dietary Polyphenols and Methylxanthines in Normal and Malignant Mammary Tissues From Breast Cancer Patients
NCT03482401CI-TRIAL-00047084POLYSENcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim is to characterise the metabolic profiling of dietary polyphenols in normal and malignant breast tissues from breast cancer patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Polyphenol | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Polyphenol group
- description
- Patients consumed a polyphenol-rich dietary supplement (commercial lemon, orange, pomegranate, olive, grape, cocoa, curcuma and broccoli extracts), mainly rich in simple phenolics such as hydroxytyrosol and the polyphenols procyanidins, hesperidin, eriocitrin, curcumin, resveratrol, punicalagin and ellagic acid. Cocoa extract also contains the methylxanthines theobromine and caffeine.
- interventionNames
- Dietary Supplement: Polyphenol
- type
- NO_INTERVENTION
- label
- Control group
- description
- Participating patients did not consume the supplement but provided biological samples to the trial
Primary outcomes (1)
- measure
- Quantification of dietary polyphenols and methylxanthines in breast tissues
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Eligible patients are those over 18 years with a newly biopsy-confirmed breast cancer, programmed surgery at least 3 days after the recruitment and no neoadjuvant treatment. Exclusion Criteria: * Suspected intolerance to any component of fruits or vegetables. * Neoadjuvant chemo- or radiotherapy. * Urgent surgery (less than 3 days after the recruitment). * Patient under 18 years. * Patient with breast adenoma.
References
Publications (0)
Data not yet available
No reference posted for this study.