Clinical trial · Interventional
Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Breast Surgery
NCT03480958CI-TRIAL-00034592completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Postoperative analgesia in breast surgery is a difficult and overworked issue due to etensive surgery and complex innervation of the breast. Erector spinae plane block (ESB) is a new defined and promising regional anesthesia technique for thoracic analgesia. Main purpose of this study is to compare the analgesic effect of ultrasound guided ESB with thoracic paravertebral block - the golden standard method for postoperative regional analgesia technique in breast surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Erector Spinae Plane Block | Other | — | UNRESOLVED |
| Intravenous morphine patient controlled device | Device | — | UNRESOLVED |
| Thoracic Paravertebral Block | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- ESP group
- description
- Erector Spinae Plane Block administered group
- interventionNames
- Device: Intravenous morphine patient controlled device
- Other: Erector Spinae Plane Block
- type
- ACTIVE_COMPARATOR
- label
- TPVB group
- description
- Thoracic Paravertebral Block administered group
- interventionNames
- Device: Intravenous morphine patient controlled device
- Other: Thoracic Paravertebral Block
- type
- OTHER
- label
- Control Group
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 25 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 25-70 years of agge * ASA I-II * Undergoing elective breast cancer surgery Exclusion Criteria: * obesity (body mass index \>35 kg/m2) * infection of the skin at the site of needle puncture area * patients with known allergies to any of the study drugs * coagulopathy * recent use of analgesic drugs
References
Publications (1)
- DERIVEDGurkan Y, Aksu C, Kus A, Yorukoglu UH. Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial. J Clin Anesth. 2020 Feb;59:84-88. doi: 10.1016/j.jclinane.2019.06.036. Epub 2019 Jul 4. PMID 31280100