Clinical trial · Observational
Electronic Cigarette Use During Pregnancy
NCT03480373CI-TRIAL-00069811completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2. To compare toxicant exposure and birth outcomes among infants born to pregnant women who use e-cigs compared to women who smoke conventional cigarettes. Aim 3. To explore potential mechanisms by which e-cigs could influence birth weight.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cigarette Smoking-Related Carcinoma | Cigarette Smoking-Related Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To compare the overall toxicant exposure in pregnant women who use electronic cigarettes compared to women who smoke conventional cigarettes.
- timeFrame
- 9 months
- description
- The overall toxicant exposure will be measured at each trimester and adjusted for potential confounding covariates. A multivariate analysis of variance (MANOVA) with repeated measures will be used to evaluate the pregnant women who use electronic cigarettes compared to women who smoke conventional cigarettes at each trimester.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 16 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: 1. cigarette smokers who exclusively smoke conventional cigarettes daily, or who use e-cigs daily, or who use either product daily and the other product at least weekly. 2. Participant is ≤ 24 weeks gestation for conventional smokers and ≤ 36 weeks gestation for e-cig users or dual users. 3. at least 16 years of age 4. able to speak English or Spanish; 5. able to read and sign consent form 6. intent to carry pregnancy to term. Exclusion Criteria: 1. current drug or alcohol abuse or dependence (other than methadone or buprenorphine maintenance) 2. participant uses combustible marijuana more than 3 times per week (use of edibles/oils is permitted 3. unstable psychiatric disorder 4. unstable medical problems (e.g., pre-eclampsia, threatened abortion, hyperemesis gravidarum) 5. known congenital abnormality 6. Regular use of tobacco products other than conventional or e-cigs
References
Publications (0)
Data not yet available
No reference posted for this study.