Clinical trial · Observational
Comparative Study in Oral, Breast Approach and Open Thyroidectomy
Comparative Study of Surgical Results in Endoscopic Thyroidectomy Via Oral Approach, Via Breast Approach and Conventional Open Thyroidectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Purpose: Total endoscopic thyroidectomy including oral approach and breast approach has excellent cosmetic and several functional results. Many patients, especially women, undergoing thyroid surgery are concerned about the postoperative cosmetic appearance of the neck. The procedure of total endoscopic thyroidectomy by breast approach only left three incisions, while by oral approach did not leave any incisions in the body surface, which is scarless in the neck, involved with a higher cosmetic result. However, the long-term property evaluation of total endoscopic thyroidectomy was not confirmed. The purpose of our study was to evaluate the surgical results of total endoscopic thyroidectomy (transoral approach and breast approach) versus conventional open thyroidectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Neoplasms | Thyroid Gland Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Thyroid Surgical Methods | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Conventional Open
- description
- Conventional open thyroidectomy group (thyroid neoplasms patients who underwent conventional thyroidectomy procedure with or without postoperative central node dissection)
- interventionNames
- Procedure: Thyroid Surgical Methods
- label
- Transoral Endoscopic Surgery
- description
- Transoral endoscopic thyroidectomy via vestibular approach group (thyroid neoplasms patients who underwent conventional thyroidectomy procedure with or without postoperative central node dissection)
- interventionNames
- Procedure: Thyroid Surgical Methods
- label
- Endoscopic Thyroidectomy via Breast
- description
- Endoscopic thyroidectomy via breast approach or bilateral areola approach group (thyroid neoplasms patients who underwent conventional thyroidectomy procedure with or without postoperative central node dissection)
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age: 15\~55 years old; 2. Type: Differentiated thyroid carcinoma, diameter ≤ 2cm, cN0 or cN1a, M0; 3. Thyroid lobe was less than the second degree enlargement; 4. Thyroid benign goiter, and the diameter ≤ 6cm Exclusion Criteria: 1. Combine the surgical history of mandibular, oral, facial, or neck; 2. It was shown by preoperative radiological examination that the thyroid cancer has local invasion, N1b, or distant metastasis. 3. Thyroid lobe was more than the third degree enlargement 4. Any medical history that probably interfere the test results or increase the disease risks 5. The patient's compliance is not very well, and cannot work as the doctors asked
References
Publications (2)
- RESULTWang Y, Yu X, Wang P, Miao C, Xie Q, Yan H, Zhao Q, Zhang M, Xiang C. Implementation of Intraoperative Neuromonitoring for Transoral Endoscopic Thyroid Surgery: A Preliminary Report. J Laparoendosc Adv Surg Tech A. 2016 Dec;26(12):965-971. doi: 10.1089/lap.2016.0291. Epub 2016 Sep 1. PMID 27585396
- DERIVEDZhu R, Yue N, Hong Y, Ye Q, Han Z, Luo Z, Xie C, Yan H, Yu X. Ectopic parathyroid adenomas in primary hyperparathyroidism: anatomical classifications, localization strategies, and case series. Int J Surg. 2026 Jan 12;112(4):9958-74. doi: 10.1097/JS9.0000000000004578. Online ahead of print. PMID 41417934