Clinical trial · Interventional
L-Carnitine and Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovary Syndrome
NCT03476356CI-TRIAL-00032225completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study to assess the efficacy of adding L-carnitine to clomiphene citrate for increasing the ovulation and the pregnancy rate in women with PCOS.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| oral carnitine supplementation | Drug | — | UNRESOLVED |
| oral clomiphene citrate | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group L
- description
- This group will receive oral clomiphene citrate (Clomid, Global Napi Pharmaceuticals (GNP), Egypt) (50 mg tablet, two times per day) from the third day of the cycle until the seventh day of the cycle plus oral carnitine supplementation (Carnivita Forte, Eva Pharma, Egypt) (1g tablet, three times per day) from the third day of the cycle until the day of the pregnancy test.
- interventionNames
- Drug: oral clomiphene citrate
- Drug: oral carnitine supplementation
- type
- ACTIVE_COMPARATOR
- label
- Group C
- description
- This group will receive oral clomiphene citrate only (Clomid, Global Napi Pharmaceuticals (GNP), Egypt) (50 mg tablet, two times per day) from the third day of the cycle until the seventh day of the cycle.
- interventionNames
- Drug: oral clomiphene citrate
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 35 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age ranging from 18-35 years. 2. Normal Hysterosalpingo-graphy (HSG). 3. Normal Semen analysis of the husband. 4. Diagnosed with PCOS based on the (ESHRE/ASRM) guidelines criteria (Rotterdam Criteria 2003). Exclusion Criteria: 1. Patient's refusal. 2. Male factors of infertility and/or abnormal HSG. 3. Hyperprolactinemia (prolactin ≥ 22 ng/dl). 4. FSH on day 3 \> 15 mIU/mL. 5. Gross ovarian pathology diagnosed by ultrasound.
References
Publications (0)
Data not yet available
No reference posted for this study.