Clinical trial · Interventional
Intracorporeal vs Extracorporeal Urinary Diversion After Robot Assisted Radical Cystectomy
Randomized Clinical Trial of Intracorporeal vs Extracorporeal Urinary Diversion After Robot Assisted Radical Cystectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Intracorporeal urinary diversion (ICD) provides superior postoperative outcomes compared to extracorporeal urinary diversion (ECD). The investigators' hypothesis that ICD may provide clinical benefit is based on principles of less bowel and ureteral handling, superior operating room workflow, less exposure to the external environment, and optimal visualization with ICD while utilizing a smaller incision compared to ECD. ICD should have less bowel-related complications, lower pain scores allowing patients to be discharged from the hospital sooner and regain functional independence more quickly.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Extracorporeal Urinary Diversion | Procedure | — | UNRESOLVED |
| Intracorporal Urinary Diversion | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Extracorporeal Urinary Diversion (ECD)
- description
- Participants will be randomized to receiving ECD after scheduled Robotic Assisted Radical Cystectomy (RARC).
- interventionNames
- Procedure: Extracorporeal Urinary Diversion
- type
- EXPERIMENTAL
- label
- Intracorporal Urinary Diversion (ICD)
- description
- Participants will be randomized to receiving ICD after scheduled Robotic Assisted Radical Cystectomy (RARC).
- interventionNames
- Procedure: Intracorporal Urinary Diversion
Primary outcomes (1)
- measure
- 90-day Major Post-Operative Complication Rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Biopsy-proven urothelial cancer being considered for RARC. * Clinical stage T1-T4, N0-1, M0 or refractory carcinoma in situ. * Subject must be already scheduled to have a RARC at the discretion of the surgeon and with the patient's agreement. Exclusion Criteria: * Inability to give informed consent * Prior major abdominal and pelvic open surgical procedures that would preclude a safe robotic approach, as determined by the treating surgeon. * At the discretion of the treating surgeon, any pre-existing condition such as severe chronic obstructive pulmonary disease that precludes a safe initiation or maintenance of pneumoperitoneum over a prolonged period of time and during surgery. * Age \<18 or \>99 years.
References
Publications (0)
Data not yet available