Clinical trial · Interventional
Effects of Succinylcholine on Nonintubated Thoracoscopic Surgery
Can Mini-dose Succinylcholine Accelerate Lung Collapse and Intrathoracic Nerve Blocks During Nonintubated Thoracoscopic Surgery? A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A safe and effective surgical environment is important for nonintubated thoracoscopic surgery. The investigators hypothesize that mini-dose succinylcholine can induce ultra-short period of apnea, by which the ventilatory responses to open pneumothorax were abolished and may facilitate rapid and satisfying collapse of the operated lung during nonintubated thoracoscopic surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Atelectasis | — | UNRESOLVED | — |
| Complication of Ventilation Therapy | — | UNRESOLVED | — |
| Tumor of Lung Parenchyma | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Placebo | Drug | — | UNRESOLVED |
| Succinylcholine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Nonintubated VATS succinylcholine
- description
- Nonintubated VATS using mini-dose succinylcholine in the beginning of open pneumothorax
- interventionNames
- Drug: Succinylcholine
- type
- PLACEBO_COMPARATOR
- label
- Nonintubated VATS placebo
- description
- Nonintubated VATS not using succinylcholine in the beginning of open pneumothorax
- interventionNames
- Drug: Placebo
Primary outcomes (1)
- measure
- Quality of lung collapse
- timeFrame
- 20 minutes
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Adults patients with lung tumors and elective for unilateral thoracoscopic surgery. Exclusion Criteria: * Over weighted, body mass index \> 26 kg/m2. * Previous thoracic surgery on the attempted operative side. * Hypoventilation syndrome requiring positive pressure ventilatory support or oxygen at home. * Relevant systemic disease, including heart failure, liver failure, renal failure with an American Society of Anesthesiologists (ASA) class above 3. * Difficult airway management. * Pregnancy. * Contraindications for succinylcholine, including family history of suspicious malignant hyperthermia, hyperkalemia, or other neuromuscular diseases.
References
Publications (0)
Data not yet available