Clinical trial · Interventional
Impact of Adjuvant Chemotherapy on the Quality of Life of Patients Treated for Stage II / III Endometrial Cancer
NCT03466788CI-TRIAL-00099260EndoQOLcompletedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Through this study, The investigator believe to evaluate the impact in terms of overall quality of life of adjuvant chemotherapy in patients with locally advanced endometrial cancer at a distance from their care
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chemotherapy Effect | — | UNRESOLVED | — |
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Self questionnaires of quality of life and living conditions | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Patients treated with chemotherapy
- interventionNames
- Other: Self questionnaires of quality of life and living conditions
- type
- OTHER
- label
- Patients not treated with chemotherapy
- interventionNames
- Other: Self questionnaires of quality of life and living conditions
Primary outcomes (1)
- measure
- The Impact in Terms of Overall Quality of Life of Adjuvant Chemotherapy by the QLQ-C30 Questionnaire
- timeFrame
- 2 years after chemotherapy
- description
- The Quality of life questionnaire (QLQ-C30) contains 29 items dealing with fatigue, pain, nausea and vomiting, general condition and social, emotional and cognitive functions. It is currently used in many clinical trials in oncology. Here is the glodal health status scale of the QLQ-C30 questionnaire, ranging from 0 to 100, with high score indicating good quality of life.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: For all patients: * Women over 18 years of age, with histologically confirmed histologic type 1 or type 2 endometrial adenocarcinoma, with FIGO postoperative II or III stage operated between 2011 and 2015, with at least 2 years of follow-up compared to the last course of chemotherapy; * Recommended surgery such as hysterectomy and bilateral salpingo-oophorectomy, non-mandatory surgical nodal staging; * Pelvic radiotherapy +/- lumbar-aortic irradiation, optional brachytherapy; * No recurrence of endometrial cancer at baseline; * Absence of evolutionary neurological antecedent (multiple sclerosis, neurodegenerative pathology ...); * Absence of progressive psychiatric pathology (i.e. psychiatric hospitalization, bipolar disorder, schizophrenia, personality disorders ...); * No opposition to the collection of data; * Patient deemed fit to answer a written questionnaire. For the patient in the chemotherapy group - Chemotherapy after surgery that can be performed before or after radiotherapy Exclusion Criteria: For all patients: * Sarcoma or carcinosarcoma; * Stage FIGO I or IV; * Macroscopic tumor residue after surgery; * Recurrence of endometrial cancer or diagnosis of any other cancerous pathology after diagnosis of endometrial cancer (except non-melanotic skin tumors with complete excision), within 5 years; * drug use; * Abuse of alcohol. For the patient in the chemotherapy group * Chemotherapy before surgery; * Chemotherapy concomitant with radiotherapy For the patient in the group without chemotherapy \- Chemotherapy whether before or after surgery
References
Publications (0)
Data not yet available
No reference posted for this study.