Clinical trial · Interventional
Effects of Prehabilitation and Early Mobilization for Patients Undergoing Pancreas Surgery.
Effekt av Prehabilitering Och Extra Tidig Mobilisering Efter öppen Pankreas Kirurgi
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Open upper gastrointestinal surgery includes surgery in the upper abdomen such as ventricular, duodenal, pancreatic and biliary tract surgery. After upper abdominal surgery there is a risk of gastrointestinal and cardiopulmonary complications. There is currently insufficient knowledge about the effect of prehabilitation and extra early postoperative mobilization in upper pancreatic surgery. This study's aim is to evaluate the effect of prehabilitation and extra early mobilization. The study includes two substudies: 1. A prospective cohort of 75 patients undergoing pancreatic surgery after a prehabilitation program will be compared to 75 historical controls. Primary outcome is postoperative complications. 2. A randomized controlled trial based on 72 patients undergoing pancreatic studying the effect of extra early rehabilitation. The intervention group will be mobilized to bedside, standing or sitting in armchair \<6 hours after surgery, ie 3-4 hours after arrival at the Postoperative Department (PIVA). The control group will be mobilized according to routine i.e. the morning after surgery. Primary outcome is PaO2.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreas Cancer | Pancreatic Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Extra early mobilization | Other | — | UNRESOLVED |
| Prehabilitation | Other | — | UNRESOLVED |
| Routine care | Other | — | UNRESOLVED |
| Standard mobilization | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Prospective cohort-prehabilitation
- description
- A prehabilitation program including advice about diet, increased physical activity and cessation of smoking and drinking alcohol.
- interventionNames
- Other: Prehabilitation
- type
- ACTIVE_COMPARATOR
- label
- Retrospective cohort
- description
- Routine care before the prehabilitation program was introduced
- interventionNames
- Other: Routine care
- type
- EXPERIMENTAL
- label
- Extra early mobilization
- description
- Mobilization the day of surgery
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled to undergo pancreatic surgery Exclusion Criteria in substudy b: * Preoperative injury or disease making it impossible to perform the intervention
References
Publications (1)
- DERIVEDFagevik Olsen M, Becovic S, Dean E. Short-term effects of mobilization on oxygenation in patients after open surgery for pancreatic cancer: a randomized controlled trial. BMC Surg. 2021 Apr 7;21(1):185. doi: 10.1186/s12893-021-01187-2. PMID 33827537