Clinical trial · Observational
Serum-Ascites Albumin Gradient Analysis in Cancer Patients in Palliative Care
NCT03463655CI-TRIAL-00032054AGASA-SPunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites. The etiology of ascites in cancer patients is multifactorial, particularly by hepatic invasion that can lead to ascites loaded with albumin. Ascites punctures therefore lead to undernutrition, recurrent early ascites by decreasing the oncotic pressure by hypo albuminemia and a state of anasarca affecting the quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Cancer in a Palliative Situation With Ascites | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cirrhotic albumin | Diagnostic Test | — | UNRESOLVED |
| serum albumin | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- solid cancer in a palliative situation with ascites
- description
- Patient over the age of 18, followed for a solid cancer in a palliative metastatic situation, having had a puncture of ascites.
- interventionNames
- Diagnostic Test: cirrhotic albumin
- Diagnostic Test: serum albumin
Primary outcomes (1)
- measure
- Serum-Ascites Albumin Gradient Prevalence
- timeFrame
- 3 months
- description
- Elevated Serum-Ascites Albumin Gradient Prevalence in Palliative Cancer Patients
Secondary outcomes (1)
- measure
- Metastatic sites
- timeFrame
- 3 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient over 18 years of age followed for a solid cancer in a palliative metastatic situation who had a puncture of ascites. Exclusion Criteria: * Minor patient * Known cirrhosis
References
Publications (3)
- BACKGROUNDCarrier P, Jacques J, Debette-Gratien M, Legros R, Sarabi M, Vidal E, Sautereau D, Bezanahary H, Ly KH, Loustaud-Ratti V. [Non-cirrhotic ascites: pathophysiology, diagnosis and etiology]. Rev Med Interne. 2014 Jun;35(6):365-71. doi: 10.1016/j.revmed.2013.12.001. Epub 2014 Jan 6. French. PMID 24406314
- BACKGROUNDGuide pratique des soins palliatifs Edition A.P.E.S. (2008)
- BACKGROUNDAyantunde AA, Parsons SL. Pattern and prognostic factors in patients with malignant ascites: a retrospective study. Ann Oncol. 2007 May;18(5):945-9. doi: 10.1093/annonc/mdl499. Epub 2007 Feb 13. PMID 17298959