Clinical trial · Interventional
Effects of Increased Physical Activity Before Thoracoabdominal Esophageal Surgery
Effekt av ökad Fysisk träning i Samband Med Thorakoabdominell Esofaguskirurgi
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Thoracoabdominal oesophageal resection for cancer is a procedure with high risks for complications, and patients' preoperative status is a crucial factor for outcome. There are only a few studies that evaluate the effect of preoperative intervention, including physical exercises and breathing exercises, after this type of surgery. The aim of the study is therefore to evaluate the effect of a training intervention before resection of the oesophagus. One hundred patients scheduled for oesophagus resection according to Ivor-Lewis from five different hospitals in Sweden will be included. The patients will be randomized to an intervention group or a control group. The training intervention starts directly after preoperative radiotherapy and chemotherapy are given and lasts until three months postoperatively. Intervention includes increased physical activity, strength training and respiratory muscle training. At inclusion and three months after discharge, the patients will undergo tests of physical function and lung function. In addition, they will fill in questionnaires concerning level of physical function, level of physical activity and quality of life. These questionnaires will also be answered one year after surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Oesophageal Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pretraining | Other | — | UNRESOLVED |
| Usual care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Pretraining
- description
- Increased physical activity daily Daily strength training Daily inspiratory and expiratory muscle training Standard care during hospital stay and continued training after discharge.
- interventionNames
- Other: Pretraining
- type
- ACTIVE_COMPARATOR
- label
- Usual care treatment
- description
- Standard care including preoperative information and postoperative breathing exercises and mobilization during hospital stay.
- interventionNames
- Other: Usual care
Primary outcomes (1)
- measure
- 6 minutes walk test
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled to undergo thoracoabdominal oesophagus resection at one of the five included centra Exclusion Criteria: * \< two weeks between inclusion and surgery * benign reason for surgery * difficulties in speaking and reading Swedish * other injury or disease limiting the ability to perform the intervention.
References
Publications (1)
- DERIVEDFagevik Olsen M, Lothgren S, Trolle U, Elf E, Toomvali-Petersson S, Hermansson M, Hammerlid E, Smedh U. Positive effects of a perioperative training intervention in Ivor Lewis oesophageal surgery: a randomised, controlled multicentre trial. BMC Surg. 2025 Dec 11;26(1):34. doi: 10.1186/s12893-025-03416-4. PMID 41372748