Clinical trial · Interventional
Effects of Open Thoracic Paravertebral Block on Postoperative Analgesia
Effects of Open Thoracic Paravertebral Block on Postoperative Analgesia in Patients Undergoing Open Pulmonary Lobectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study was aimed to assess the effects of open thoracic paravertebral block on postoperative analgesia in patients undergoing open pulmonary lobectomy under general anesthesia. Then, A total of 90 patients with American Society of Anesthesiologists (ASA) scores of Ⅰ or Ⅱ, scheduled for open pulmonary lobectomy under propofol - remifentanil total intravenous anaesthesia, were randomly divided into PCIA group (group G), Ultrasound-guided TPVB combined with PCIA group (group U), and open TPVB combined with PCIA group (group E).Finally, the study find that Open TPVB can provided satisfactory analgesia for patients undergoing open pulmonary lobectomy under general anesthesia, and the analgesia efficacy was equivalent to the TPVB under ultrasound guidance,which should be popularized.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Open TPVB | Combination Product | — | UNRESOLVED |
| placebo | Other | — | UNRESOLVED |
| Ultrasound-guided TPVB | Combination Product | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- PLACEBO_COMPARATOR
- label
- Placebo group (group G)
- interventionNames
- Other: placebo
- type
- ACTIVE_COMPARATOR
- label
- Ultrasound-guided TPVB group (group U)
- interventionNames
- Combination Product: Ultrasound-guided TPVB
- type
- EXPERIMENTAL
- label
- open TPVB group(group E)
- interventionNames
- Combination Product: Open TPVB
Primary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 35 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * with American Society of Anesthesiologists physical status Ⅰor Ⅱ * aged 35 - 75 years old * with body mass index of 20 - 25 kg／m2, * scheduled for open pulmonary lobectomy under general anaesthesia at the First Affiliated Hospital of Kunming Medical University Exclusion Criteria: * cardiovascular and/or cerebrovascular disease; * diabetes; pre-existing liver, lung or kidney dysfunction; * bilateral surgery; take operations again within 48 h after the surgery; * with serious pulmonary infection and coagulation dysfunction
References
Publications (0)
Data not yet available