Clinical trial · Interventional
Oncological Outcome of Contralateral Submental Artery Island Flap Versus Primary Closure in Tongue Squamous Cell Carcinoma
Oncological Outcome of Contralateral Submental Artery Island Flap Versus Primary Closure in Tongue Squamous Cell Carcinoma (Randomize Noninferiority Clinical Trial)
NCT03440151CI-TRIAL-00044647unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare the oncological and functional results of the contralateral submental flap with primary closure for reconstruction of tongue squamous cell carcinoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tongue Squamous Cell Carcinoma | Tongue Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| contralateral submental flap for tongue cancer defect | Procedure | — | UNRESOLVED |
| primary closure for tongue cancer defect | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- contralateral submental flap for tongue cancer defect
- interventionNames
- Procedure: contralateral submental flap for tongue cancer defect
- type
- ACTIVE_COMPARATOR
- label
- primary closure for tongue cancer defect
- interventionNames
- Procedure: primary closure for tongue cancer defect
Primary outcomes (1)
- measure
- local recurrence
- timeFrame
- at least one year post operative
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patient with T1\&T2 tongue squamous cell carcinoma. Exclusion Criteria: * Patients with contralateral N positive. * Patients with previous neck surgery that interrupt contralateral facial artery or vein. * Patients with prior radiotherapy to the neck. * Patients with lesions crossing the midline, or those reaching the base of tongue requiring total glossectomy. * Patients second primary tumors at the time of diagnosis. * Patient with recurrent tongue squamous cell carcinoma.
References
Publications (0)
Data not yet available
No reference posted for this study.