Clinical trial · Interventional
RCT of Ballon Technique VS Selective Ophthalmic Artery Infusion For the Retinoblastoma Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Retinoblastoma is the most common intraocular tumor in children..IAC--Targeted Treatment for Intraocular Retinoblastoma,Is minimally invasive procedure that infuse chemotherapy select into the ophthalmic artery, its can increasing the drug concentration reaching the tumor and reducing systemic toxicity compared with traditional intravenous treatment.: one is Ballon technique , another is selective ophthalmic artery infusion.This study evaluates the difference of Ballon technique and selective ophthalmic artery infusion effect in the treatment of retinoblastoma. Half of participants will receive, Ballon technique while the other half will receive selective ophthalmic artery infusion
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ballon Technique | — | UNRESOLVED | — |
| IAC | Intermediate Atypical Prostate Carcinoma | ALIAS | 0.90 |
| Retinoblastoma | Retinoblastoma | ONTOLOGY_EXACT | 0.98 |
| Selective Ophthalmic Artery Infusion | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ballon Technique | Device | — | UNRESOLVED |
| SOAI | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Ballon Technique group
- description
- Intervention：Ballon Technique
- interventionNames
- Device: Ballon Technique
- type
- ACTIVE_COMPARATOR
- label
- SOAI group
- description
- Intervention：Selective Ophthalmic Artery Infusion
- interventionNames
- Device: SOAI
Primary outcomes (1)
- measure
- Globe salvage rate (Eyes saved/Eyes treated)
- timeFrame
- Three years from intervention
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Month
- Maximum age
- 10 Years
Show eligibility criteria text
Inclusion Criteria: 1. No age limit, no gender limit, monocular or binocular affected; 2. New diagnosed cases, without any previous treatment; 3. Clinical diagnosed as retinoblastoma, and in group C, D or E according to IIRC standard; Binocular affected with one eye enucleated; 4. Normal bone marrow function 5. Normal liver function 6. Normal kidney function 7. Normal coagulation function 8. To be willing to take part in the clinical trial and sign the informed consent form; 9. To be willing to have these tumor sites surgically removed and do the follow up accordingly. Exclusion Criteria: 1. Diagnosis is not clear; 2. With other sever ocular diseases (for example: neovascular glaucoma, iris neovascularization); 3. With sever systemic diseases, include abnormal liver or kidney function, abnormal routine blood test or coagulation function, congenital heart diseases and dysaudia; 4. Took part in other clinical study within 3 months; 5. Refuse to take part in this clinical study; 6. Is not willing to do the follow up accordingly or follow up less than 2 times.
References
Publications (0)
Data not yet available