Clinical trial · Observational
Normal Saline Vrs Balanced i.v. Fluids in Neurosurgery
Comparison of Normal Saline and Balanced Crystalloid Intravenous Therapy During Neurosurgery
NCT03429127CI-TRIAL-00038208unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study was to investigate whether the balanced fluids therapy change plasma osmolality in neurosurgical procedures due to brain tumors, meningeomas and arterio-venous malformation.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Benign Neoplasms | Benign Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Vascular Malformations, Brain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Balanced fluid | Other | — | UNRESOLVED |
| Normal saline | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Normal saline fluid group
- description
- The patients in this group will receive up to 2000 ml of normal saline during neurosurgical operation.
- interventionNames
- Other: Normal saline
- label
- Balanced fluid group
- description
- The patients in this group will receive up to 2000 ml of balanced fluids during neurosurgical operation.
- interventionNames
- Other: Balanced fluid
Primary outcomes (1)
- measure
- Changes in acid base pH status
- timeFrame
- During operation and immediately after operation
- description
- Changes in acid base pH status after each 500 ml of normal saline vrs. balanced fluid
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with brain tumor, meningeomas and vascular malformation. Exclusion Criteria: * Patients with signs of elevated intracranial pressure; History of kidney disease, History of heart disease
References
Publications (0)
Data not yet available
No reference posted for this study.