Clinical trial · Observational
Role of Percutaneous Vertebroplasty in Treatment of Vertebral Tumors
NCT03427632CI-TRIAL-00031610PVPunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Percutaneous vertebroplasty is a new technique to strengthen bone and reduce pain for patients with vertebral tumors
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Tumor | Bone Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bone Cements | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- percutaneous Vertebroplasty
- description
- patients meet the inclusion and exclusion criteria will be subjected to percutaneous vertebroplasty receiving bone cement (Polymethyl methacrylate)
- interventionNames
- Drug: Bone Cements
Primary outcomes (1)
- measure
- pain relief
- timeFrame
- immediate
- description
- reduction of spine pain following the injection of bone cement in the tumor according to Numeric Rating Scale, Improvement will be considered if NRS score decrease ≧ 20% after PVP
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Spinal instability * Pain with movement * Multiple level involvement * Expected survival 3-6 months Exclusion Criteria: * Absolute * Asymptomatic * improving on medical treatment without worsening of the collapse. * infection local or systemic * uncorrectable coagulopathy * Allergy to bone cement or contrast media * Relative * Radicular pain * Tumor extension inside the vertebral canal or cord compression * Fracture of the posterior column * Sclerotic metastasis * Diffuse metastases
References
Publications (4)
- BACKGROUNDAlvarez L, Perez-Higueras A, Quinones D, Calvo E, Rossi RE. Vertebroplasty in the treatment of vertebral tumors: postprocedural outcome and quality of life. Eur Spine J. 2003 Aug;12(4):356-60. doi: 10.1007/s00586-003-0525-z. Epub 2003 Mar 22. PMID 12687441
- BACKGROUNDMelton LJ 3rd, Kyle RA, Achenbach SJ, Oberg AL, Rajkumar SV. Fracture risk with multiple myeloma: a population-based study. J Bone Miner Res. 2005 Mar;20(3):487-93. doi: 10.1359/JBMR.041131. Epub 2004 Nov 29. PMID 15746994
- BACKGROUNDWenger M, Markwalder TM. Re: Percutaneous vertebroplasty for pain relief and spinal stabilization (Spine 2000; 25: 923-8). Spine (Phila Pa 1976). 2000 Nov 15;25(22):2968-9. doi: 10.1097/00007632-200011150-00022. No abstract available. PMID 11074686
- BACKGROUNDTsoumakidou G, Too CW, Koch G, Caudrelier J, Cazzato RL, Garnon J, Gangi A. CIRSE Guidelines on Percutaneous Vertebral Augmentation. Cardiovasc Intervent Radiol. 2017 Mar;40(3):331-342. doi: 10.1007/s00270-017-1574-8. Epub 2017 Jan 19. PMID 28105496