Clinical trial · Interventional
Three-port Versus Conventional Laparoscopic Surgery for Colorectal Cancer
Single-center Prospective Randomized Controlled Study of the Three-port Laparoscopic Surgery Versus Conventional Laparoscopic Surgery for Colorectal Cancer
NCT03426514CI-TRIAL-00043376unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to evaluate the short-term and long-term results after three-port laparoscopic surgery for colorectal cancer（TLSC） compared with conventional laparoscopic surgery for colorectal cancer（CLSC）.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional Laparoscopic Surgery | Procedure | — | UNRESOLVED |
| Three-port Laparoscopic Surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Three-port Laparoscopic Surgery
- description
- Patients with colorectal cancer undergo three-port laparoscopic surgery.
- interventionNames
- Procedure: Three-port Laparoscopic Surgery
- type
- EXPERIMENTAL
- label
- Conventional Laparoscopic Surgery
- description
- Patients with colorectal cancer undergo conventional laparoscopic surgery（4 or more ports）.
- interventionNames
- Procedure: Conventional Laparoscopic Surgery
Primary outcomes (1)
- measure
- Early morbidity rate
- timeFrame
- 30 days after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Body mass index (BMI) \<30 kg/m2 * Tumor located in colon and high rectum (the lower border of the tumor is above the peritoneal reflection) * Pathological colorectal carcinoma * Clinically diagnosed cT1-4aN0-2 M0 lesions according to the 7th Edition of AJCC Cancer Staging Manual with or without neoadjuvant therapeutic history * ECOG score is 0-1 * ASA score is Ⅰ-Ⅲ * Informed consent Exclusion Criteria: * Previous gastrointestinal surgery * History of inflammatory bowel disease * History of familial adenomatous polyposis（FAP） * Pregnant woman or lactating woman * Severe mental disease * Intolerance of surgery for severe comorbidities * Emergency operation due to complication (bleeding, perforation or obstruction) caused by colorectal cancer * Requirement of simultaneous surgery for other disease
References
Publications (2)
- BACKGROUNDTawfik Amin A, Elsaba TM, Amira G. Three ports laparoscopic resection for colorectal cancer: a step on refining of reduced port surgery. ISRN Surg. 2014 Mar 12;2014:781549. doi: 10.1155/2014/781549. eCollection 2014. PMID 25006515
- BACKGROUNDSeow-En I, Tan KY, Mohd Daud MA, Seow-Choen F. Traditional laparoscopic colorectal resections can be performed effectively using a three-port technique. Tech Coloproctol. 2011 Mar;15(1):91-3. doi: 10.1007/s10151-010-0660-6. Epub 2011 Jan 14. No abstract available. PMID 21234638