Clinical trial · Observational
Systematic Review and Meta-analysis of Cereal or Grain Consumption and Gastric Cancer
Cereal or Grain Consumption and Gastric Cancer Risk: a Systematic Review and Meta-analysis of Observational Studies
NCT03419663CI-TRIAL-00031531GCcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This project involved a systematic literature review of published trials of cereal or grain in relation to the risk of gastric cancer. Data was extracted from the publications on PubMed, EMBASE, Cochrane Library.A traditional meta-analysis, subgroup analysis, and heterogeneity was conducted on the extracted data.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cereal or grain consumption | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- gastric cancer
- interventionNames
- Dietary Supplement: cereal or grain consumption
Primary outcomes (1)
- measure
- the relationship between overall cereal consumption and gastric cancer occurance
- timeFrame
- up to 2 years
- description
- perform a pooled analysis of included studies with OR through STATA 12.0
Secondary outcomes (3)
- measure
- the relationship between whole grain and gastric cancer occurance
- timeFrame
- up to 2 years
- description
- perform a subgroup analysis to summarize the related OR through STATA 12.0
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * a case-control studies or a cohort study * investigate the association between cereal or grain intake and GC occurrence * report an odds ratio (OR) or relative risk (RR) with corresponding 95% confidence intervals (CI) * provide sufficient data to estimate OR or RR Exclusion Criteria: * Non-human studies * GC mortality-based cohort studies
References
Publications (1)
- DERIVEDXu Y, Yang J, Du L, Li K, Zhou Y. Association of whole grain, refined grain, and cereal consumption with gastric cancer risk: A meta-analysis of observational studies. Food Sci Nutr. 2018 Nov 11;7(1):256-265. doi: 10.1002/fsn3.878. eCollection 2019 Jan. PMID 30680179