Clinical trial · Interventional
The "PC-LIGHT" Study
Systematic Light Exposure to Prevent Fatigue in Prostate Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Fatigue due to cancer and its treatment (for example, radiation therapy) can interfere with quality of life and can linger long after treatment has ended, yet research examining preventative approaches has produced limited clinical benefit. The proposed study will provide information about systematic light exposure for the prevention of fatigue in prostate cancer patients undergoing radiation therapy and will investigate how it works. This study would facilitate the development of this potential preventative treatment, giving health care providers and cancer survivors a much-needed tool to help with cancer-related fatigue.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Depression | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
| Quality of Life | — | UNRESOLVED | — |
| Sleep | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Comparison systematic light exposure | Device | — | UNRESOLVED |
| Intervention systematic light exposure | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention light
- description
- 30 minutes of intervention systematic light exposure daily for the course of radiation therapy (approximately 8 weeks).
- interventionNames
- Device: Intervention systematic light exposure
- type
- ACTIVE_COMPARATOR
- label
- Comparison light
- description
- 30 minutes of comparison systematic light exposure daily for the course of radiation therapy (approximately 8 weeks).
- interventionNames
- Device: Comparison systematic light exposure
Primary outcomes (4)
- measure
- Fatigue FACIT-Fatigue scores
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Have been diagnosed with clinical localized prostate cancer, * Are about to begin external beam radiation therapy (RT) for prostate cancer, * Are 18 years of age or older, * Are able to speak or read English, * Have internet access. Exclusion Criteria: * History of light therapy use (e.g. systematic light exposure), * Active infection * History of chronic fatigue disorders * Confounding underlying medical illnesses such as significant pre-existing anemia (Hb\<10 gm/dl) * Diagnosed or suspected psychiatric or medical condition that might contribute to fatigue (other than those caused by the cancer or its treatment) * Hypothyroidism or documented history of hypothyroidism on thyroid replacement hormone within \<3 months of initiating RT * History of bipolar disorder or mania * History of seasonal affective disorder * Diagnosed sleep apnea, restless legs, or other sleep disorders (not including insomnia) known to affect fatigue * Use of photosensitizing medication * Plans to travel across more than 2 time zones during the study * Shift worker * Adults unable to consent, individuals who are not yet adults, pregnant women, and prisoners will be excluded from the study
References
Publications (0)
Data not yet available